← Back to Search

Alcohol-PTSD-PFI (AP-PFI) for Problem Drinking

Verified Trial
N/A
Waitlist Available
Research Sponsored by University of Houston
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
You drink alcohol at least weekly.
You are at least 21 years old.
Timeline
Screening 1 day
Treatment Varies
Follow Up 1 day
Awards & highlights

Study Summary

This trial is testing the efficacy of a novel computer based PFI to help reduce drinking in people who have subclinical PTSD and anxiety sensitivity.

Eligible Conditions
  • Problem Drinking
  • Alcoholism
  • Anxiety Disorders
  • Generalized Anxiety Disorder
  • Post-Traumatic Stress Disorder

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
You drink alcohol every week.
Select...
You must be 21 years old or older to participate.
Select...
You have recently been through an extremely difficult or upsetting experience.
Select...
We want to know if you feel worried or nervous.
Select...
You are able to speak and understand English well.
Select...
You can come to the study appointments in person.

Timeline

Screening ~ 1 day
Treatment ~ Varies
Follow Up ~1 day
This trial's timeline: 1 day for screening, Varies for treatment, and 1 day for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Changes in PTSD symptom severity: The Posttraumatic Stress Disorder Checklist for DSM-5 (PCL-5)
Changes in anxiety sensitivity levels: Short Scale Anxiety Sensitivity Index (SSASI)
Changes in frequency and quantity of alcohol consumption: Timeline Follow-Back
+2 more
Secondary outcome measures
Evaluate the feasibility and acceptability of AP-PFI vs. C-PFI: Treatment Credibility/Expectancy Questionnaire
Evaluate the moderating role of family history of AUD on PTSD and alcohol-related outcomes

Trial Design

2Treatment groups
Experimental Treatment
Group I: Alcohol-PTSD-PFI (AP-PFI)Experimental Treatment1 Intervention
Hazardous drinkers with at least subclinical PTSD and elevated AS (N=100) recruited from the community will be randomly assigned to receive Alcohol-PTSD-PFI (AP-PFI) or an active comparison control condition (C-PFI).
Group II: Active Comparison Condition (C-PFI)Experimental Treatment1 Intervention
Participants in the time-matched comparison condition will receive personalized feedback on alcohol use but will not receive PTSD or AS-related personalized feedback. C-PFI will include alcohol-focused components identical to those provided in AP-PFI (e.g., alcohol profiles, normative feedback). Therefore, it will be possible to isolate the impact of personalized PTSD and AS feedback versus personalized alcohol feedback.

Find a Location

Who is running the clinical trial?

University of HoustonLead Sponsor
147 Previous Clinical Trials
47,452 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there opportunities for people to join this clinical experiment currently?

"As indicated on clinicaltrials.gov, this medical research is not currently seeking volunteers. The details of the trial were posted on July 1st 2022 and most recently revised 20 days later – however 411 other studies remain open for recruitment at present."

Answered by AI

Who else is applying?

What state do they live in?
California
North Carolina
Other
Texas
How old are they?
18 - 65
What site did they apply to?
Anxiety and Health Research Lab- Substance Use Treatment Clinic
What portion of applicants met pre-screening criteria?
Did not meet criteria
Met criteria
How many prior treatments have patients received?
3+
1
0

Why did patients apply to this trial?

That I'm ready to stop drinking. I have tried various treatments to no avail. Thank you.
PatientReceived 2+ prior treatments
I tried quitting by don't have the courage or the will power. I've survived two life changing traumas and I've turned to alcohol to maintain.
PatientReceived 1 prior treatment
I used to take antidepressants but they didn’t seem to have any effects on me positive or negative. I occasionally use alcohol at times to cope with life situations. I’m hoping to find some type of solution for my ongoing struggles.
PatientReceived 2+ prior treatments

What questions have other patients asked about this trial?

How long do screenings take? Will I ever be able to live a normal productive life?
PatientReceived 2+ prior treatments

How responsive is this trial?

Most responsive sites:
  1. Anxiety and Health Research Lab- Substance Use Treatment Clinic: < 24 hours
Average response time
  • < 2 Days
Typically responds via
Phone Call
Email
Recent research and studies
clinicaltrials.govStudy
PFI Hazardous Drinkers With Subclinical PTSD
Michael J. Zvolensky, Ph.D. 2022. "PFI Hazardous Drinkers With Subclinical PTSD". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04836442.
~36 spots leftby Apr 2025
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top