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Behavioral Intervention

Written Exposure Therapy (WISE) for Post-Traumatic Stress Disorder (WISE Trial)

N/A
Waitlist Available
Led By Samuel McLean, MD, MPH
Research Sponsored by University of North Carolina, Chapel Hill
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline, 3-months
Awards & highlights

WISE Trial Summary

This trial is testing whether a written exposure therapy can help reduce posttraumatic stress symptoms in people who have been in a car collision.

Eligible Conditions
  • Post Traumatic Stress Disorder

WISE Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline, 3-months
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, 3-months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in PTSD Symptom Scores from Baseline to Month 1
Change in PTSD Symptom Scores from Baseline to Month 2
Change in PTSD Symptom Scores from Baseline to Month 3
Secondary outcome measures
Change in Depressive Symptoms Score
Change in Pain Symptom Score
Change in Somatic Symptom Score

WISE Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: Written Exposure TherapyExperimental Treatment1 Intervention
Group II: Non-emotional WritingPlacebo Group1 Intervention
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Written Exposure Therapy (WISE)
2022
N/A
~50

Find a Location

Who is running the clinical trial?

University of Florida HealthOTHER
9 Previous Clinical Trials
4,392 Total Patients Enrolled
Indiana UniversityOTHER
980 Previous Clinical Trials
983,120 Total Patients Enrolled
Washington University School of MedicineOTHER
1,931 Previous Clinical Trials
2,299,668 Total Patients Enrolled

Media Library

Written Exposure Therapy (WISE) (Behavioral Intervention) Clinical Trial Eligibility Overview. Trial Name: NCT05390775 — N/A
Post-Traumatic Stress Disorder Research Study Groups: Non-emotional Writing, Written Exposure Therapy
Post-Traumatic Stress Disorder Clinical Trial 2023: Written Exposure Therapy (WISE) Highlights & Side Effects. Trial Name: NCT05390775 — N/A
Written Exposure Therapy (WISE) (Behavioral Intervention) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05390775 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Can you give me an estimate of how many hospitals are conducting this trial at the moment?

"The trial is being conducted at Indiana University, Washington University, and University of Massachusetts Chan Medical School. Additionally, there are 5 other sites where the trial is running."

Answered by AI
Recent research and studies
clinicaltrials.govStudy
Written Exposure Therapy to Improve Lives After Stress Exposure
2022. "Written Exposure Therapy to Improve Lives After Stress Exposure". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05390775.
~15 spots leftby Apr 2025
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