Early Adenotonsillectomy (eAT) for Sleep Apnea (PATS Trial)

"459 minors aged between 3 and 12, who struggle with respiratory aspiration, have been accepted into this clinical trial. In addition to age criteria, participants must also satisfy the following conditions: Tonsillar hypertrophy ≥2 based on a standardized 0-4 scale; regular nocturnal snoring for at least three months that occurs more than half of sleep time on at least three nights per week; Polysomnogram (PSG) confirming an obstructive apnea index (OAI) <1/hour and apnea-hypopnea index (AHI) ≤3/hour without oxygen desaturation below 90"

"This particular trial is seeking patients in the 3-12 age range, while there are 46 trials for minors and 274 studies targeting seniors."

"As reflected on clinicaltrials.gov, this medical experiment is no longer accepting patients. It was initially posted on June 1st 2016 and edited most recently on July 18th 2022. Despite the closure of recruitment for this trial, there are still 337 other trials actively enrolling participants at present."

"Currently, this clinical experiment is being carried out at 7 separate locations. These sites are located in Norfolk, Philadelphia and Ann Arbor with 4 other centres scattered across the country. It would be beneficial to select a local clinic to spare patients from long-distance travel should they choose to take part."

"The primary endpoint assessed over the course of a year is Change from baseline in Go-No-Go (GNG) signal detection parameter d'-prime. Secondary outcomes include GNG Continuous Performance Task (CPT) inhibitory control parameter d', Height, and BRIEF meta-cognition and emotional regulation summary scores and subscales.."