EUREKA Intervention for Skin Cancer Prevention

(EUREKA Trial)

Overseen By Tammy Stump, PhD

Age: < 18

Sex: Any

Trial Phase: Academic

Sponsor: University of Utah

Disqualifiers: Non-English speakers, Pacemaker, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: Unknown

200 Participants Needed

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial tests a new smartphone app, the EUREKA Intervention, designed to help children and their parents reduce sun exposure and prevent sunburns. The app provides feedback on UV (ultraviolet) exposure and suggests protective measures, such as using sunscreen or wearing hats. It suits children aged 8 to 17 in Utah who have experienced a sunburn in the past year and do not consistently use sun protection. Participants will use a sensor to track UV exposure and need a smartphone to access the app. As an unphased trial, this study offers participants the opportunity to contribute to innovative research that could improve sun protection strategies for children.

What prior data suggests that this intervention is safe for children?

Research has shown that the EUREKA Intervention aims to lower exposure to ultraviolet radiation (UVR), which is crucial for preventing skin cancer. This program uses a smartphone app to provide feedback on UVR exposure and encourage sun safety habits, such as using sunscreen and wearing protective clothing.

The EUREKA Intervention is safe because it primarily offers guidance through an app. No harmful side effects are known from using this type of digital tool. Instead, it helps users develop better sun safety habits, which are essential for preventing skin cancer. The app promotes healthy behavior without introducing new medication or invasive treatments, making it a well-accepted approach. ^{1 2 3 4 5}

Why are researchers excited about this trial?

Researchers are excited about the EUREKA Intervention for skin cancer prevention because it offers a novel approach by using a smartphone app to deliver personalized assessments and interventions. Unlike traditional methods that often rely on in-person consultations or generic information, this app provides tailored guidance over 21 days, making it more accessible and engaging for users. The digital format also allows for real-time feedback and adjustments, potentially improving adherence and effectiveness in preventing skin cancer.

What evidence suggests that the EUREKA Intervention is effective for skin cancer prevention?

Research has shown that reducing exposure to ultraviolet (UV) rays is crucial for preventing skin cancer. In this trial, participants will use the EUREKA app, which studies have demonstrated helps people lower their UV exposure and improve sun safety habits, such as using sunscreen and wearing protective clothing. These habits reduce the risk of sunburns and, over time, skin cancer. Digital tools effectively reach many people, especially young ones, to encourage better sun protection. Early evidence suggests that technology like smartphone apps can successfully promote these protective behaviors. ^{1 4 6 7 8}

Who Is on the Research Team?

Tammy Stump, PhD

Principal Investigator

Huntsman Cancer Institute/ University of Utah

Are You a Good Fit for This Trial?

This trial is for kids aged 8-17 in Utah who've had a sunburn in the past year and don't always use sun protection like sunscreen or clothing. Their caregivers must be over 18, able to use a smartphone, willing to download an app that tracks UV exposure, and responsible for the child's health tasks. Kids with prior skin cancer diagnoses can't join.

Inclusion Criteria

I am 18 years old or older.

I am the main person taking care of the child's health needs.

I have and can use a smartphone.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

1-2 weeks

Intervention

Participants use a SmartPhone app to receive feedback on UVR exposure and sun protection strategies

3 weeks

Daily app usage

Follow-up

Participants are monitored for sun protection behaviors and UVR exposure after the intervention

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

• EUREKA Intervention

Trial Overview The EUREKA study tests a new way to help kids avoid too much sun using feedback from a smartphone app about their UV exposure. The goal is to improve how often they use sunscreen and wear protective clothes, aiming to reduce sunburns.

How Is the Trial Designed?

Group I: EUREKA Intervention Experimental Treatment 1 Intervention

This arm will utilize a SmartPhone app to deliver assessments and interventions for 21 days

Who Is Running the Clinical Trial?

University of Utah

Lead Sponsor

Trials

1,169

Recruited

1,623,000+

Citations

1. clinicaltrials.gov clinicaltrials.gov/study/NCT07204704

EUREKA: Evaluating Ultraviolet Radiation Exposure in ... Ultraviolet radiation (UVR) exposure is the primary modifiable risk factor for melanoma. Adoption of sun protective behaviors, such as sunscreen use, are ...

2. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov/26810358/

Efficacy of an Intervention to Alter Skin Cancer Risk Behaviors ... Results: For the intervention arm, there were significant decreases in UV exposure and increases in skin protection at both follow-up time ...

3. australian.museum australian.museum/blog/science/leading-efforts-to-improve-early-detection-of-melanoma/

Leading efforts to improve early detection of melanoma If shown to be effective, enhanced imaging technologies and AI-assisted diagnostics may lead to quicker, more accurate diagnoses, allowing for ...

4. mdpi.com mdpi.com/2072-6694/17/21/3473

The Impact of Multidisciplinary Research on Progress in ... We explore both individual- and population-level contributions to skin cancer prevention and highlight how the contributions of many fields across both these ...

5. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov/40131334/

Digital Skin Cancer Risk Reduction Interventions for Young ... Impact: This digital intervention offers the potential to reduce skin cancer risk in a large population of US young adults.

6. trialx.com trialx.com/clinical-trials/listings/308393/eureka-evaluating-ultraviolet-radiation-exposure-in-kids-for-adaptive-intervention/

EUREKA: Evaluating Ultraviolet Radiation Exposure in ... Ultraviolet radiation (UVR) exposure is the primary modifiable risk factor for melanoma. Adoption of sun protective behaviors, such as sunscreen ...

7. app.trialscreen.org app.trialscreen.org/trials/eureka-evaluating-ultraviolet-radiation-exposure-kids-adaptive-intervention-trial-nct07204704

Evaluating Ultraviolet Radiation Exposure in Kids for ... EUREKA: A study testing a smartphone app to help children and ... skin cancer prevention, and potentially develop better long-term sun safety habits.

8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov/articles/PMC10502947/

Increasing Skin Cancer Prevention in Young Adults Increasing skin cancer prevention in young adults: the cumulative impact of personalized UV photography and MC1R genetic testing.