eBook + CHOICES Intervention for Sickle Cell Disease
(CHOICES3 Trial)
Trial Summary
What is the purpose of this trial?
The study will use web-based data collection (SCKnowIQ) and intervention delivery strategies enhanced by nudges and tailored boosters in a sample of 430 adult men and women, aged 18-45 yr with SCD (Sickle Cell Disease) or SCT (Sickle Cell Trait), at-risk, and planning within 2 years to have a child free of SCD.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications.
What data supports the effectiveness of the CHOICES treatment for Sickle Cell Disease?
The CHOICES intervention is a web-based educational tool that helps people with sickle cell disease make informed decisions about reproductive health, which is crucial for planning and managing their condition. While the study focuses on reproductive health, it suggests that providing targeted information can empower patients to make better health decisions, potentially improving overall management of sickle cell disease.12345
Is the CHOICES Intervention safe for people with sickle cell disease?
How is the CHOICES treatment for sickle cell disease different from other treatments?
The CHOICES treatment is unique because it is an online educational program designed to help individuals with sickle cell disease or trait make informed reproductive decisions, focusing on understanding genetic inheritance and parenting options, rather than directly treating the disease itself.17101112
Research Team
Diana Wilkie, PhD
Principal Investigator
University of Florida
Eligibility Criteria
This trial is for adults aged 18-45 with Sickle Cell Disease (SCD) or Sickle Cell Trait (SCT), who can read and speak English, want to conceive within the next two years, and aim to have a child free of SCD. It's not open to those who've been in CHOICES studies before, are unable to complete study tasks, or cannot have children due to medical reasons.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive web-based reproductive education and tailored interventions for sickle cell disease or trait
Follow-up
Participants are monitored for knowledge retention and behavior changes after intervention
Treatment Details
Interventions
- CHOICES
- eBook
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Florida
Lead Sponsor
National Human Genome Research Institute (NHGRI)
Collaborator