← Back to Search

eBook + CHOICES Intervention for Sickle Cell Disease (CHOICES3 Trial)

N/A
Recruiting
Led By Diana Wilkie, PhD
Research Sponsored by University of Florida
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
At-risk for having a child with SCD
18 to 45 years
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline up to 24 months
Awards & highlights

CHOICES3 Trial Summary

This trial will test whether nudges and tailored boosters can help people with sickle cell disease or thalassemia have a child free of their condition.

Who is the study for?
This trial is for adults aged 18-45 with Sickle Cell Disease (SCD) or Sickle Cell Trait (SCT), who can read and speak English, want to conceive within the next two years, and aim to have a child free of SCD. It's not open to those who've been in CHOICES studies before, are unable to complete study tasks, or cannot have children due to medical reasons.Check my eligibility
What is being tested?
The CHOICES3 trial is testing a web-based program designed to help people with SCD/SCT make informed decisions about having children. Participants will use an online platform offering educational content and personalized support strategies aimed at reducing the risk of conceiving a child with SCD.See study design
What are the potential side effects?
Since this intervention involves educational content delivered through an eBook rather than medication, there are no direct physical side effects expected from participating in this clinical trial.

CHOICES3 Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I am at risk of having a child with sickle cell disease.
Select...
I am between 18 and 45 years old.
Select...
I have been diagnosed with sickle cell disease or carry the sickle cell trait.

CHOICES3 Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline up to 24 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline up to 24 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Sickle Cell Reproductive Health Knowledge

CHOICES3 Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: CHOICESExperimental Treatment1 Intervention
Experimental arm: receives the web-based reproductive education for individuals with sickle cell disease or sickle cell trait
Group II: eBook (electronic-Book)Placebo Group1 Intervention
Control arm with eBook education focused on sickle cell disease and sickle cell trait.

Find a Location

Who is running the clinical trial?

University of FloridaLead Sponsor
1,338 Previous Clinical Trials
714,810 Total Patients Enrolled
National Human Genome Research Institute (NHGRI)NIH
262 Previous Clinical Trials
282,520 Total Patients Enrolled
Diana Wilkie, PhDPrincipal InvestigatorUniversity of Florida

Media Library

CHOICES Clinical Trial Eligibility Overview. Trial Name: NCT05292781 — N/A
Sickle Cell Disease Research Study Groups: CHOICES, eBook (electronic-Book)
Sickle Cell Disease Clinical Trial 2023: CHOICES Highlights & Side Effects. Trial Name: NCT05292781 — N/A
CHOICES 2023 Treatment Timeline for Medical Study. Trial Name: NCT05292781 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are participants being recruited presently for this research initiative?

"According to information available on clinicaltrials.gov, this particular medical study is open for recruitment and has been since June 1st 2022. The trial was recently updated on May 31st of the same year."

Answered by AI

Is this investigation open to persons of an advanced age?

"This experiment has a strict age limit of 18 to 35, with separate trials being conducted for those under 18 and over 65. Consequently, 132 studies are running for minors while 88 cater to the elderly population."

Answered by AI

May I be included in this medical experiment?

"This clinical trial requires all applicants to have the sickle cell trait, and they must be aged between 18-35. Currently, this medical study is seeking out a total of 506 individuals for participation."

Answered by AI

What is the sample size of the participants in this clinical trial?

"Absolutely, according to the information found on clinicaltrials.gov, this medical trial is currently enrolling patients from a single site. The study was first advertised on June 1st 2022 and has been updated as recently as May 31st 2022; 506 people are needed for participation in total."

Answered by AI
~253 spots leftby Jun 2025