Prednisone for Vasectomy Reversal
The Impact of Prednisone on Semen Parameters and Pregnancy Rates Post Vasectomy Reversal
See full descriptionAbout the trial for Vasectomy Reversal
Treatment Groups
This trial involves 3 different treatments. Prednisone is the primary treatment being studied. Participants will be divided into 3 treatment groups. There is no placebo group. The treatments being tested are in Phase 4 and have been shown to be safe and effective in humans.
About The Treatment
Side Effect Profile for Arm B (Stanford V)
Eligibility
This trial is for male patients aged 18 and older. There are 7 eligibility criteria to participate in this trial as listed below.
Approximate Timelines
Measurement Requirements
This trial is evaluating whether Prednisone will improve 1 primary outcome and 2 secondary outcomes in patients with Vasectomy Reversal. Measurement will happen over the course of Up to 1 year.
Patient Q & A Section
Can vasectomy reversal be cured?
Vasectomy reversal is well tolerated in most men, with a low incidence of complications. Most men achieve full and long-term ejaculatory function after a vasectomy reversal.
What is vasectomy reversal?
A vasectomy reversal can be performed following the diagnosis of spermatozoa in one or both seminograms. The first vasectomy reversal can be performed as early as one year after the vasectomy (if the semenographic findings in the first seminogram were abnormal).
How many people get vasectomy reversal a year in the United States?
Only half the men report undergoing a vasectomy reversal, and there is no difference in the demographics or medical indications between the two groups. Most reversal were performed in a single surgeon's ovasectomy unit. In a recent study, findings suggests that vasectomy reversals may be a relatively unexplored clinical option. However, further studies are required to confirm and expand these findings.
What causes vasectomy reversal?
Vasectomy reversal represents a challenging surgery with challenging oncological considerations and a significant risk of complications that must be weighed against the benefit of fertility in the long term. Laparoscopic vasovasostomy may help reduce the operative risk of vasectomy reversal.
What are the signs of vasectomy reversal?
In this survey of men undergoing vasectomy reversal, there was no clinically visible indication of epididymal obstruction. The routine use of doppler sonography of the epididymis in all patients undergoing vasectomy reversal is highly recommended.
What are common treatments for vasectomy reversal?
Commonly used treatments for vasectomy reversal include vasovasostomy, vasotomy reversal, vasectomy reconnection, and microsurgery. Because of the lack of evidence concerning the treatment of male infertility after vasectomy reversal, patient selection to facilitate the use of one type of therapy over another should be explored.
Who should consider clinical trials for vasectomy reversal?
For this cohort, most patients who had a vasectomy reversal did not have prior vasectomy issues and only 9% had a history of prior vasectomy issues. There was no significant difference in pain, function, or sexual function scores when comparing the vasectomy reversal group to the control group at 24 months.
Has prednisone proven to be more effective than a placebo?
In a recent study, findings indicates that prednisone is not a more effective treatment than a placebo in regards to decreasing relapse rates after vasectomy reversal.
What is the average age someone gets vasectomy reversal?
About half the men who undergo vasectomy reversal are younger than 55 years of age. This is the first study to report that men who have undergone vasectomy reversal are typically younger.
Does vasectomy reversal run in families?
Although almost half of men who underwent vasectomy reversal in New York state between 1979 and 1986 were the sons of men who had undergone vasectomy reversal, and even the most conservative estimates from this study indicate a familial bias, further epidemiologic investigation is not currently warranted.
Have there been any new discoveries for treating vasectomy reversal?
There are many possible ways for vasectomy reversal, as well as some that have been used in the past. There are still no single, definitive methods of vasectomy reversal.
What does prednisone usually treat?
Prednisone can cause a number of problems, like the increase of infections, blood sugar problems, and kidney problems. A [vasectomy reversal with prednisone] treatment can resolve these problems.\n