This trial is evaluating whether PrEPmate will improve 3 primary outcomes and 3 secondary outcomes in patients with HIV Infections. Measurement will happen over the course of Adherence self-efficacy measured through 12 months.
This trial requires 300 total participants across 2 different treatment groups
This trial involves 2 different treatments. PrEPmate is the primary treatment being studied. Participants will be divided into 2 treatment groups. There is no placebo group. The treatments being tested are not being studied for commercial purposes.
"The [Federal Center for Disease Control]] estimates that at least 9% of adults have a sexually transmitted diseases in the United States. It is imperative to have a good understanding of the prevalence of sexually transmitted diseases in the United States because these rates are difficult to obtain." - Anonymous Online Contributor
"Sexual activity can be associated with the development of genital infection with sexually transmitted infections. The following sexual act associated with infection with sexually transmitted infections is unprotected oral sex: A recent history of genital injury with or without signs of infection, non-regular partner of the last partner, or a spouse with a history of HIV/AIDS. Previous infection with a sexually transmitted infection can also be associated with sexual activity associated with an increased risk of infection with sexually transmitted infections, but to less than 10%." - Anonymous Online Contributor
"STDs can be acquired from a person's partner or others close to them. Most of the STDs can be prevented through screening people for STDs who have sex with men, including HIV and other sexually transmitted diseases. Preventive interventions that do not rely on screening are not effective for preventing HIV. STDs are often spread through intercourse; condoms or abstinence are usually the most effective ways to prevent them. Many other STDs can be prevented by avoiding a sexually active lifestyle." - Anonymous Online Contributor
"Many sexual partners treat themselves with barrier contraception to prevent pregnancy, while many couples also consider partner condoms. Vaccinations are recommended for hepatitis A, typhoid, tetanus, diphtheria and pertussis. Oral sex has been shown to be a risk factor for HIV infection, but is being used as a method of transmission. Inappropriate treatment of sexually transmitted infections is a major risk factor for transmission of HIV to partners. Gender-specific preventive methods have been shown to be protective, such as male condoms. It is unclear if the use of male contraceptive condoms is safer than female barrier contraception for women at high enough risk for HIV infection." - Anonymous Online Contributor
"Most STDs begin during adolescence. Infection is not spread from one person to another. Genital infection is common and often unrecognized. Sexual partners often are a vector for STDs. Many STDs are easily preventable. STDs can be minimized by using condoms consistently, correctly and consistently during and after sexual intercourse, use of other non-penetrative male contraceptives, not having multiple sex partners and receiving regular health care.\n\nFactors that increase the likelihood that a pregnant woman will have complications: Age, preexisting chronic illnesses, chronic exposure to various types of drugs and/or pollutants like tobacco." - Anonymous Online Contributor
"It is likely that, in clinical practice, the possibility of healing STDs is minimal. Nevertheless, it is possible to prevent them in populations where they are common. Because people are very attached to the idea that they could be cured of STDs, if the notion that this is possible is raised, their fear, insecurity and mistrust are increased, leading to an increase of disease in other circumstances. This may be a barrier for implementing programmes to prevent STDs." - Anonymous Online Contributor
"There have been a small number of clinical trials carried out with "premate" as a study adjuvant. These include 2 "premate vs. placebo" trials and 3 studies using non-sterile penile implants. A systematic review and meta-analyse were also conducted in 2008 involving the study of oral premate and a meta-analysis involving premate vs placebo also yielded similar results. Oral premate did not appear to result in benefits of treating "non-infectious" symptoms for "sexually active" or "homosexual" patients." - Anonymous Online Contributor
"In the UK, most doctors treat sexually transmitted infections (STI) by using [the STI first-line treatment for men and women] or 'do no harm' practices that focus on symptomatic treatment of people without STI." - Anonymous Online Contributor
"The use of a placebo on the other hand may have an impact on the results of the study. In our study, the prevalence of genital ulcer infection was similar to the one seen with the control group. A longer duration of the study and more subjects might probably provide more reliable data. However, in conclusion, there is no definite proof of the superiority of a steroid cream preparation over a placebo in the treatment of genital ulcer on the other hand there is no proof for the superiority of one preparation over another and in the present study no conclusion can be drawn on the treatment of genital ulcer (Tab. 5, Fig. 6, Ref. 29)." - Anonymous Online Contributor
"Almost four-fifths of sexually active women reported being concerned about the possibility that they or their partner might have a STI. A significant number (22%) of women reported being “very” or “fairly” concerned about developing an STI. Women and men should be able to be adequately educated about the risk of contracting an STI, as well as risk factors for infection. Many women reported that they would definitely like to take part in a trial of an STI vaccine." - Anonymous Online Contributor
"This first cross-generational examination of the relative frequency of STD in first-degree relatives of subjects with a diagnosis of STI suggests that STDs are not significantly associated with familial occurrence of STI. In contrast, there may be a significant association between low relative frequency and a lower prevalence of a prior STD." - Anonymous Online Contributor
"More than half of sexually active young women have a sexually transmitted disease infection. In some instances, men can be found to be the primary source of infection. Most women may not be aware of the health issue. Appropriate education about safe sexual practices can be of value." - Anonymous Online Contributor