← Back to Search

Electronic Alert System for Sepsis (SEPTIC-ED Trial)

N/A

Waitlist Available

Led By Jason S Adelman, MD, MS

Research Sponsored by Columbia University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

does not have an active order for "comfort measures only"

age > 18 years-old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up up to 90 days

Awards & highlights

SEPTIC-ED Trial Summary

This trial tests if nurse and prescribing clinician alerts can help reduce time to sepsis treatment for patients in the ED.

Who is the study for?

This trial is for adults over 18 in the emergency department who meet criteria for systemic inflammatory response syndrome (SIRS) but aren't pregnant, haven't tested positive for COVID-19 recently, and aren't on comfort-only care. It excludes those already receiving sepsis treatment or enrolled in the SEPTIC study.Check my eligibility

What is being tested?

The study tests if electronic alerts to nurses and/or prescribing clinicians can speed up sepsis treatment. Patients are randomly placed into one of four groups: no alerts, nurse-only alerts, clinician-only alerts, or both nurse and clinician alerts.See study design

What are the potential side effects?

Since this trial involves electronic prompts rather than medications or procedures, traditional side effects are not a concern. However, there may be impacts on workflow or care delivery processes.

SEPTIC-ED Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I am not under care for comfort measures only.

Select...

I am older than 18 years.

SEPTIC-ED Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ up to 90 days

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~up to 90 days

This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 90 days for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Percentage of patients treated with Surviving Sepsis Campaign (SSC) hour-1 bundle

Secondary outcome measures

Adverse antibiotic events

Median number of days of hospitalization

Number of positive blood cultures

+14 more

SEPTIC-ED Trial Design

4Treatment groups

Experimental Treatment

Active Control

Group I: Prescribing clinician alertExperimental Treatment1 Intervention

Participants will receive physician alert.

Group II: Nurse alert and prescribing clinician alertExperimental Treatment2 Interventions

Participants will receive physician alert and RN alert.

Group III: Nurse alertExperimental Treatment1 Intervention

Participants will receive RN alert.

Group IV: No alertActive Control1 Intervention

Participants will receive no physician alert or registered nurse (RN) alert.

0 / 2Eligibility criteria met

Find a Location

Who is running the clinical trial?

Columbia UniversityLead Sponsor

1,433 Previous Clinical Trials

2,433,009 Total Patients Enrolled

Jason S Adelman, MD, MSPrincipal InvestigatorColumbia University

4 Previous Clinical Trials

27,305 Total Patients Enrolled

Benjamin L Ranard, MD, MSHPStudy DirectorColumbia University

1 Previous Clinical Trials

7,200 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is recruitment for this trial ongoing at present?

"As reported on clinicaltrials.gov, this specific research endeavour is no longer recruiting patients after having been initially posted November 1st 2023 and last updated October 31st 2023. However, there are currently 398 other trials that are actively seeking enrolment."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Sepsis Electronic Prompting for Timely Intervention and Care for Emergency Department Patients

Jason Adelman 2023. "Sepsis Electronic Prompting for Timely Intervention and Care for Emergency Department Patients". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT06117605.

All > Sepsis