Seizure Control for Brain Tumor

RA
AA
Overseen ByAshley Aaroe, MD
Age: Any Age
Sex: Any
Trial Phase: Academic
Sponsor: M.D. Anderson Cancer Center
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to explore how seizures change over time in people with low-grade gliomas (a type of brain tumor) and their treatments. By tracking these seizures, the researchers hope to identify symptoms or triggers earlier, potentially leading to quicker and better care. Participants will complete a brief survey about their seizures during each clinic visit. This trial might suit adults with primary brain tumors who have a history of seizures related to their tumor and are currently receiving treatment. As a Phase 2 trial, this research focuses on measuring the treatment's effectiveness in an initial, smaller group, offering participants a chance to contribute to important findings.

Do I need to stop my current medications for the trial?

The trial information does not specify if you need to stop taking your current medications. It might be best to discuss this with the trial coordinators or your doctor.

Why are researchers excited about this trial?

Researchers are excited about this trial because it explores seizure control as a novel metric for evaluating the effectiveness of tumor treatments in patients with low-grade glioma. Unlike traditional methods that primarily focus on tumor size changes, this approach emphasizes the impact on seizure activity, which is a significant concern for patients. By using a simple, quick survey that patients complete during clinic visits, this method aims to provide a more patient-centered evaluation of treatment success, potentially leading to more personalized and effective care strategies.

Who Is on the Research Team?

AA

Ashley Aaroe, MD

Principal Investigator

M.D. Anderson Cancer Center

Are You a Good Fit for This Trial?

Inclusion Criteria

Adult patients
History of seizures secondary to brain tumor On tumor directed treatment
Magnetic resonance imaging (MRI) within 2 weeks of clinic visit where seizure assessment takes place
See 1 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Observational

Patients complete a seizure assessment survey over 5 minutes at each clinic visit

Up to 2 years
Regular clinic visits

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Survey Administration
How Is the Trial Designed?
1Treatment groups
Experimental Treatment
Group I: Observational (survey)Experimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

M.D. Anderson Cancer Center

Lead Sponsor

Trials
3,107
Recruited
1,813,000+

National Cancer Institute (NCI)

Collaborator

Trials
14,080
Recruited
41,180,000+
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