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Lung volume recruitment for Multiple Sclerosis

N/A
Waitlist Available
Led By Douglas A McKim, MD
Research Sponsored by Ottawa Hospital Research Institute
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
History of multiple sclerosis, diagnosed by a neurologist in accordance with the 2010 McDonald criteria
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline, 2, 4, 6 and 9 months
Awards & highlights

Study Summary

Multiple sclerosis is a neurological disease that can affect lung function and cough efficacy. This pilot study will examine whether the lung volume recruitment technique can slow down the decline in lung function and cough.

Eligible Conditions
  • Multiple Sclerosis

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline, 2, 4, 6 and 9 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, 2, 4, 6 and 9 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Rate of decline of FVC (forced vital capacity)
Secondary outcome measures
Change from baseline in FVC at 2, 4, 6 and 9 months
Change from baseline in peak cough flow at 2, 4, 6 and 9 months
Rate of decline of peak cough flow

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Lung volume recruitmentExperimental Treatment1 Intervention
Lung volume recruitment twice daily for 9 months
Group II: Standard careActive Control1 Intervention
Standard care

Find a Location

Who is running the clinical trial?

The Ottawa HospitalOTHER
93 Previous Clinical Trials
62,883 Total Patients Enrolled
3 Trials studying Multiple Sclerosis
152 Patients Enrolled for Multiple Sclerosis
Ottawa Hospital Research InstituteLead Sponsor
563 Previous Clinical Trials
2,787,682 Total Patients Enrolled
2 Trials studying Multiple Sclerosis
55 Patients Enrolled for Multiple Sclerosis
Douglas A McKim, MDPrincipal InvestigatorThe Ottawa Hospital

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Lung Volume Recruitment for Lung Function and Cough Impairment in Multiple Sclerosis
2013. "Lung Volume Recruitment for Lung Function and Cough Impairment in Multiple Sclerosis". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT01891071.
All > Lung
~3 spots leftby May 2025
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