36 Participants Needed

Music Video Game for Schizophrenia

Recruiting at 1 trial location
JJ
Overseen ByJoshua J Chiappelli, MD
Age: < 65
Sex: Any
Trial Phase: Academic
Sponsor: University of Maryland, Baltimore

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial explores the use of a music video game to enhance cognitive function in individuals with schizophrenia. The focus is on improving brain communication through a game similar to "Guitar Hero," which may address cognitive issues associated with slower thinking in schizophrenia. The study seeks participants diagnosed with schizophrenia or similar conditions who have good hand mobility and are comfortable with MRI scans. As an unphased trial, it offers a unique opportunity to explore innovative methods for enhancing brain function.

Will I have to stop taking my current medications?

The trial information does not specify whether you need to stop taking your current medications.

What prior data suggests that this music video game is safe for individuals with schizophrenia?

Research has shown that playing music video games, like "Guitar Hero," is generally safe for most people. These games are popular and used by many, including those with health issues. Because music video games don't involve taking medicine or undergoing medical procedures, they usually present fewer risks and side effects.

Specific data on using music video games to help treat schizophrenia is not yet available, as the trial is in an early stage. However, music video games, as a type of digital activity, are not known to cause harm.

Overall, playing a music video game is likely well-tolerated because they are designed to be fun and engaging.12345

Why are researchers excited about this trial?

Researchers are excited about using a music video game for schizophrenia treatment because it offers a completely different approach compared to traditional methods like antipsychotic medications and cognitive behavioral therapy. Unlike these standard treatments, which can have significant side effects or require lengthy therapy sessions, this video game-based approach uses engaging gameplay to potentially improve cognitive functions and emotional processing in a fun, interactive way. By incorporating a familiar and enjoyable activity like playing "Guitar Hero," this method could enhance motivation and adherence to therapy, making it a promising, non-invasive alternative for patients.

What evidence suggests that this music video game is effective for schizophrenia?

Research has shown that playing video games can help people with schizophrenia improve their thinking and social skills. In this trial, participants in the active training arm will engage in sessions using the music video game 'Guitar Hero'. Music video games might enhance the brain's white matter, which is crucial for fast communication between different brain regions. This communication often slows in people with schizophrenia. Studies suggest that video games can offer a low-cost way to address mental health challenges, making music video games a promising option for improving cognitive issues in schizophrenia.16789

Are You a Good Fit for This Trial?

This trial is for individuals aged 15-45 who have been diagnosed with schizophrenia or related disorders and can give informed consent. It's not suitable for those with hand-use limitations, MRI contraindications like metal implants or claustrophobia, or a recent substance use disorder.

Inclusion Criteria

I am between 15 and 45 years old.
Able to provide informed consent
I have been diagnosed with a schizophrenia spectrum disorder.

Exclusion Criteria

I have a condition like arthritis that limits my hand use.
Contraindications to MRI (metal implants, claustrophobia)
Active or recent (within 6 months) substance use disorder other than nicotine

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Active Training

Participants undergo training sessions involving playing the video game 'Guitar Hero' to study white matter structure changes

3 weeks

Observation Training

Participants in the placebo group do not receive active training but are observed for changes in white matter microstructure

3 weeks

Follow-up

Participants are monitored for safety and effectiveness after training

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Music video game
Trial Overview The study investigates if playing a music video game can improve the brain's white matter structure in people with schizophrenia. This could potentially enhance their cognitive functions, particularly processing speed by simulating playing an instrument.
How Is the Trial Designed?
2Treatment groups
Active Control
Placebo Group
Group I: Active trainingActive Control1 Intervention
Group II: Observation trainingPlacebo Group1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of Maryland, Baltimore

Lead Sponsor

Trials
729
Recruited
540,000+

Citations

Music Video Game for SchizophreniaThe study investigates if playing a music video game can improve the brain's white matter structure in people with schizophrenia.
The impact of video gaming on cognitive functioning of people ...Video gaming is a promising intervention for cognitive and social impairment in patients with schizophrenia.
Exploring Gamification and Serious Games for Mental HealthThis shows that video games can be tried as a low-cost rehabilitation among schizophrenia patients [17]. Role of serious video games in ...
Gaming Your Mental Health: A Narrative Review on Mitigating ...Counter striking psychosis: commercial video games as potential treatment in schizophrenia? A systematic review of neuroimaging studies ...
Combination of a Serious Game Application and Direct ...A serious game which introduces four characters who suffer from various mental disorders (schizophrenia, depression, agoraphobia, and bipolar ...
Depiction of mental illness and psychiatry in popular video ...75% of this content depict characters with a mental illness in a negative way. The most common type of portrayal is a schizophrenia-like illness ...
https://dash.harvard.edu/server/api/core/bitstream...... safety, future of work, creativity, entertainment ... outcomes, and offer rich and engaging interactive ... data. There is a risk of undermining ...
OUT OF THE SHADOWS AT LAST1.3.3 Safe and Adequate Housing. Katherine and Scott explained that individuals with a mental illness often also face difficulty in finding safe, adequate ...
Syllabus and ProceedingsSchizophrenia®: Big Data for Psychosis Prediction. Chair: Sarah E ... schizophrenia, and then discuss new results from current research ...
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