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20 Hz rTMS for Schizophrenia

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Schizophrenia20 Hz rTMS - Device
Eligibility
18 - 40
All Sexes
What conditions do you have?
Select

Study Summary

This trial will test the effects of a new treatment for psychosis on the brain.

Treatment Effectiveness

Effectiveness Progress

1 of 3

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Study Objectives

2 Primary · 0 Secondary · Reporting Duration: 3 weeks

3 weeks
Anterior Cingulate Cortex Activation
Cognitive Control Network Functional Connectivity

Trial Safety

Safety Progress

1 of 3

Similar Trials

1
CYP3A5 expressers with chronic kidney disease
1
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2
Levetiracetam (LEV) 500 mg

Trial Design

2 Treatment Groups

20 Hz rTMS targeting the LSPC
1 of 2
20 Hz rTMS targeting the LDLPFC
1 of 2

Experimental Treatment

20 Total Participants · 2 Treatment Groups

Primary Treatment: 20 Hz rTMS · No Placebo Group · N/A

20 Hz rTMS targeting the LSPC
Device
Experimental Group · 1 Intervention: 20 Hz rTMS · Intervention Types: Device
20 Hz rTMS targeting the LDLPFC
Device
Experimental Group · 1 Intervention: 20 Hz rTMS · Intervention Types: Device
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
20 Hz rTMS
2019
N/A
~30

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: 3 weeks

Who is running the clinical trial?

Indiana UniversityLead Sponsor
878 Previous Clinical Trials
760,015 Total Patients Enrolled
14 Trials studying Schizophrenia
1,002 Patients Enrolled for Schizophrenia
Michael M Francis, MDPrincipal InvestigatorIndiana University

Eligibility Criteria

Age 18 - 40 · All Participants · 7 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
, the risk of long-term disability was increased more than threefold in patients with first-episode psychosis The risk of long-term disability was increased more than threefold in patients with first-episode psychosis within 10 years of illness onset.
I am willing and able to adhere to the study schedule.
The MINI is a short, structured psychiatric interview that is used to diagnose mental disorders
or other outpatient setting Participants must not have had an intensification of their psychiatric care in the 4 weeks prior to randomization, as judged by the investigator
The patient must have been taking the same antipsychotic medication for at least four weeks before they are randomized into the study
You are between the ages of 18 and 40.
References

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