Objective auto-regulation training for Sarcopenia

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
University of Saskatchewan, Saskatoon, CanadaSarcopeniaResistance training - Behavioral
Eligibility
18+
All Sexes
What conditions do you have?
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Study Summary

This research study is comparing the effect of traditional standardized, subjective auto-regulated, and objective auto-regulated resistance training on physiological adaptations and performance measures in adults aged 50 years or older. Traditional standardized resistance training involves prescribing resistance training as a percentage of an individual's one-repetition maximum (i.e., the maximal weight they can lift one time). Auto-regulated resistance training involves adjusting resistance training based on an individual's performance during the session. Subjective auto-regulation involves the resistance trainee providing a subjective rating of perceived exertion based on repetitions in reserve (on a scale from 1 - 10) to adjust the resistance training prescription. A rating of perceived exertion of 10 would mean that the resistance trainee believes that they have provided maximal effort and believes that they could not have performed an additional repetition during the set nor increased the load. Objective auto-regulation involves adjusting the resistance training prescription from a linear position transducer (a device that has a string that attaches to the barbell and provides a velocity value on each repetition). A slower velocity value means a higher perceived exertion and load used, whereas a faster velocity value means a lower perceived exertion and load used.

Treatment Effectiveness

Study Objectives

2 Primary · 6 Secondary · Reporting Duration: Baseline, 12 weeks

Baseline, 12 weeks
Change from baseline for time to sit and stand from a chair five times
Knee
Muscle Tissue
Change from baseline in time to climb 10 stairs
Change from baseline in time to complete the "timed up and go" (TUG) test
Change from baseline in time to walk 10 meters
baseline, 12 weeks
Change from baseline in bench press strength
Change from baseline in squat strength

Trial Safety

Trial Design

3 Treatment Groups

Traditional standardized training
1 of 3
Objective auto-regulation training
1 of 3
Subjective auto-regulation training
1 of 3

Active Control

Experimental Treatment

30 Total Participants · 3 Treatment Groups

Primary Treatment: Objective auto-regulation training · No Placebo Group · N/A

Objective auto-regulation training
Behavioral
Experimental Group · 1 Intervention: Resistance training · Intervention Types: Behavioral
Subjective auto-regulation training
Behavioral
Experimental Group · 1 Intervention: Resistance training · Intervention Types: Behavioral
Traditional standardized training
Behavioral
ActiveComparator Group · 1 Intervention: Resistance training · Intervention Types: Behavioral
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Resistance training
2008
Completed Phase 3
~970

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: baseline, 12 weeks

Who is running the clinical trial?

University of SaskatchewanLead Sponsor
239 Previous Clinical Trials
90,349 Total Patients Enrolled
6 Trials studying Sarcopenia
551 Patients Enrolled for Sarcopenia

Eligibility Criteria

Age 18+ · All Participants · 1 Total Inclusion Criteria

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Frequently Asked Questions

Is it still possible for volunteers to join this experiment?

"Affirmative, information on clinicaltrials.gov reveals that this experiment is presently recruiting patients. It was first published on October 15th 2022 and has been updated as of October 31st 2022. 30 individuals must be recruited from one site to complete the trial." - Anonymous Online Contributor

Unverified Answer

What is the enrollment capacity for this clinical trial?

"Yes, according to clinicaltrials.gov's information, this research is currently recruiting participants; the trial was initially published on October 15th 2022 and most recently revised on October 31st 2022. The medical team requires 30 patients from 1 trial site." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.