Exercise for Sarcopenia
Trial Summary
What is the purpose of this trial?
Participants will be 60-80 y men and women who vary their physical activity (steps/day) while their lipid metabolism is studied (n=24). Thereafter, another group (n=60) will perform 6 months of exercise training focused on developing maximal cycling power, during which their changes in muscle mass and practical function will be carefully measured.
Do I need to stop my current medications for the trial?
The trial information does not specify whether you need to stop taking your current medications.
What data supports the effectiveness of the treatment Exercise, Physical Activity, Workout, Fitness Training for sarcopenia?
Is exercise safe for humans, especially older adults with sarcopenia?
Exercise, including resistance training, is generally safe for humans and can improve muscle strength, physical performance, and body composition in older adults with sarcopenia. It is considered a beneficial therapy with protective effects and is often safer and less expensive than other interventions.36789
How does exercise as a treatment for sarcopenia differ from other treatments?
Exercise is unique for treating sarcopenia because it improves muscle function by enhancing mitochondrial health, which is crucial for energy production in cells. Unlike medications, exercise can increase muscle strength and endurance without side effects, and it can be tailored to individual needs and capabilities.67101112
Eligibility Criteria
This trial is for relatively healthy men and women aged between 60-80 years who are interested in participating in an exercise program to combat muscle loss (sarcopenia) and improve heart health. Those considered relatively unhealthy cannot participate.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Baseline Activity Monitoring
Participants' daily step counts are monitored to determine the range needed to prevent impairment of fat metabolism
Exercise Training
Participants perform a 24-week exercise program focused on developing maximal cycling power to counteract sarcopenia
Follow-up
Participants are monitored for safety and effectiveness after the exercise training
Treatment Details
Interventions
- Exercise
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Texas at Austin
Lead Sponsor