Exercise for Sarcopenia
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial aims to explore how exercise affects muscle mass and overall function, with a focus on developing cycling power. Researchers are particularly interested in the impact of physical activity on lipid metabolism, or how the body processes fats, in participants. The trial suits relatively healthy men and women aged 60 to 80 who are willing to engage in a structured exercise routine. Participants will either vary their daily steps or undergo six months of power training to observe changes in their muscles and physical abilities. As an unphased trial, this study offers participants the opportunity to contribute to valuable research on exercise and aging.
Do I need to stop my current medications for the trial?
The trial information does not specify whether you need to stop taking your current medications.
What prior data suggests that exercise is safe for older adults?
Research has shown that exercise is generally safe for older adults and can help strengthen muscles. Studies have found that people who stay active or become more active have a lower risk of weak muscles and poor physical performance. This suggests that exercise could effectively manage sarcopenia, the loss of muscle mass and strength.
Exercise programs, especially those including balance training along with strength exercises, have proven effective. Moderate confidence exists that these exercises improve muscle strength and function without causing serious harm.
In summary, exercise is a well-tolerated way to improve muscle health in older adults. It is usually safe and can help reduce the risk of muscle loss and weakness.12345Why are researchers excited about this trial?
Researchers are excited about using exercise to treat sarcopenia because it targets muscle strength and mass in a natural and non-invasive way. Unlike typical treatments that might involve medication or supplements, such as hormone therapy or protein supplements, power training directly stimulates muscle fibers through physical activity. This approach not only enhances muscle function but also improves overall physical health, which is a holistic benefit that medications alone can't provide. By focusing on a six-month power training regimen, the treatment aims to deliver sustainable improvements in muscle strength and quality of life for those affected by sarcopenia.
What evidence suggests that exercise might be an effective treatment for sarcopenia?
Research has shown that exercise improves muscle strength and physical performance in people with sarcopenia, a condition that causes muscle loss with age. This trial will focus on six months of power training as the experimental treatment. Studies have found that resistance training, which involves exercises where muscles work against a weight or force, significantly increases muscle mass and strength. Reviews of multiple studies confirm that physical activity, including resistance exercises, benefits older adults by boosting their muscle strength and overall physical function. Different types of training have also improved specific abilities, like walking speed and grip strength, in older people with sarcopenia. Overall, exercise is a proven way to combat the effects of sarcopenia.13678
Are You a Good Fit for This Trial?
This trial is for relatively healthy men and women aged between 60-80 years who are interested in participating in an exercise program to combat muscle loss (sarcopenia) and improve heart health. Those considered relatively unhealthy cannot participate.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Baseline Activity Monitoring
Participants' daily step counts are monitored to determine the range needed to prevent impairment of fat metabolism
Exercise Training
Participants perform a 24-week exercise program focused on developing maximal cycling power to counteract sarcopenia
Follow-up
Participants are monitored for safety and effectiveness after the exercise training
What Are the Treatments Tested in This Trial?
Interventions
- Exercise
Trial Overview
The study involves two parts: initially, participants will vary their daily physical activity while researchers study changes in fat metabolism. Then, a second group will undergo six months of exercise training aimed at increasing cycling power to see how it affects muscle mass and function.
How Is the Trial Designed?
1
Treatment groups
Experimental Treatment
Six months of power training
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Texas at Austin
Lead Sponsor
Published Research Related to This Trial
Citations
Effectiveness of different types of exercise based- ...
This meta-analysis supported the use of physical exercise to improve the physical performance and muscular strength of people with sarcopenia.
Effectiveness of different types of exercise based- ...
Results showed that physical activity was effective to improve the physical performance muscular strength) of older adults with sarcopenia. •. Resistance-based ...
Effects of different exercise training modes on muscle strength ...
In older people with sarcopenia, KES and GS can be improved by RT and MT, but not by WBVT. All three training modes improved TUG times, but not improved CS ...
The effect of resistance training on patients with secondary ...
RT has been proven to have a significant effect on the prevention and treatment of sarcopenia, as it enhances muscle strength, muscle mass, and ...
Exercise for sarcopenia in older people: A systematic review ...
This study aimed to compare the effectiveness of different exercise types for older adults with sarcopenia.
Association between changes in physical activity and ...
Middle-aged and older people who remain or become physically active have a lower risk of sarcopenia, poor muscle strength, and low physical performance.
Impact of physical activity on the management of sarcopenia
Physical inactivity is a major risk factor for muscle loss and weakness, which results in increased fatigability. The regular exercise is ...
Influence of exercise and nutrition on sarcopenia in ...
Abstract. This document aims to review current scientific evidence on exercise and nutrition as a treatment for sarcopenia in the context of cardiovascular.
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