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Behavioural Intervention
Exercise for Sarcopenia
N/A
Waitlist Available
Research Sponsored by Baltimore VA Medical Center
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Be older than 65 years old
Must not have
Physical impairment preventing exercise
Diagnosis of diabetes, cancer, pulmonary or renal disease
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 6 months
Awards & highlights
Summary
This trial aims to see if starting with aerobic exercise before strength training can help older adults with muscle loss due to aging. The idea is that better blood flow from aerobic exercise will make muscles respond better to strength training. Participants will start with either aerobic exercise or strength training, and their muscle size, strength, and function will be measured.
Who is the study for?
This trial is for older adults with a body mass index between 18-32.5 who have moderate sarcopenia, which means they've lost muscle mass as they've aged. They must be non-smokers and not currently exercise regularly. People with diabetes, cancer, lung or kidney diseases, or physical impairments that prevent exercising cannot participate.
What is being tested?
The study is testing if doing aerobic exercises can increase the number of small blood vessels in muscles and improve the benefits of strength training in older adults with sarcopenia to help them regain muscle mass and function.
What are the potential side effects?
Typical side effects from aerobic and strength training may include muscle soreness, fatigue, increased heart rate during exercise, joint stress, or injury if not performed correctly.
Eligibility Criteria
Exclusion Criteria
You may be eligible for the trial if you check “No” for criteria below:Select...
I cannot exercise due to a physical impairment.
Select...
I have been diagnosed with diabetes, cancer, lung, or kidney disease.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ 6 months
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~6 months
Treatment Details
Study Objectives
Study objectives can provide a clearer picture of what you can expect from a treatment.Primary study objectives
Muscle Tissue
Skeletal muscle capillarization
Secondary study objectives
Muscle strength
Skeletal muscle structure
Trial Design
2Treatment groups
Experimental Treatment
Active Control
Group I: Aerobic exercise training followed by resistance trainingExperimental Treatment2 Interventions
Participants in this arm will undergo 3 months of aerobic exercise training, followed by 3 months of strength training
Group II: Resistance training followed by aerobic exercise trainingActive Control2 Interventions
Participants in this arm will undergo 3 months of strength training, followed by 3 months of aerobic exercise training
Research Highlights
Information in this section is not a recommendation. We encourage patients to speak with their healthcare team when evaluating any treatment decision.Mechanism Of Action
Side Effect Profile
Prior Approvals
Other Research
Aerobic exercise increases skeletal muscle capillarization, enhancing blood flow and nutrient delivery to muscle tissues. This is crucial for sarcopenia patients as it supports muscle repair and growth, counteracting muscle mass loss associated with aging.
Improved capillarization also boosts cardiovascular health, which is often compromised in older adults. By enhancing muscle capillarization and cardiovascular function, aerobic exercise helps maintain muscle strength and physical function, essential for the quality of life in sarcopenia patients.
Find a Location
Who is running the clinical trial?
Baltimore VA Medical CenterLead Sponsor
32 Previous Clinical Trials
3,052 Total Patients Enrolled
2 Trials studying Sarcopenia
19 Patients Enrolled for Sarcopenia
University of Maryland, BaltimoreOTHER
706 Previous Clinical Trials
378,407 Total Patients Enrolled
3 Trials studying Sarcopenia
267 Patients Enrolled for Sarcopenia
Media Library
Eligibility Criteria:
This trial includes the following eligibility criteria:- Your body mass index (BMI) is between 18 and 32.5.You have recently participated in exercise training.I cannot exercise due to a physical impairment.I have been diagnosed with diabetes, cancer, lung, or kidney disease.You have low muscle mass for your body size.You do not smoke.
Research Study Groups:
This trial has the following groups:- Group 1: Aerobic exercise training followed by resistance training
- Group 2: Resistance training followed by aerobic exercise training
Awards:
This trial has 1 awards, including:- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
Timeline:
This trial has the following timeline:- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
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