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Behavioral Intervention

Eccentric Exercise for Sarcopenia (ARMS-II Trial)

N/A

Waitlist Available

Led By Michael Harris-Love, DSc MPT BS

Research Sponsored by VA Office of Research and Development

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up at study baseline for all subjects

Awards & highlights

ARMS-II Trial Summary

This trial is testing a new way to use ultrasound to screen for muscle conditions and a new type of exercise to help people with those conditions.

ARMS-II Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ at study baseline for all subjects, and at week 6 and 12 of the intervention period for subjects randomly assigned to an exercise group

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~at study baseline for all subjects, and at week 6 and 12 of the intervention period for subjects randomly assigned to an exercise group

This trial's timeline: 3 weeks for screening, Varies for treatment, and at study baseline for all subjects, and at week 6 and 12 of the intervention period for subjects randomly assigned to an exercise group for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Change from Baseline in Sonographic Lean Body Mass at 3 months

Secondary outcome measures

Change from Baseline in dual-energy X-ray absorptiometry (DXA) scanning at 3 months

Adipose tissue

Change from Baseline in metabolic status at 3 months

+1 more

ARMS-II Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: Eccentric ExerciseExperimental Treatment1 Intervention

Supervised strengthening exercise using eccentric muscle actions.

Group II: Concentric ExerciseActive Control1 Intervention

Supervised strengthening exercise using concentric muscle actions.

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Eccentric Exercise

2009

N/A

~150

Do I qualify?Apply below to find out

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Who is running the clinical trial?

VA Office of Research and DevelopmentLead Sponsor

1,609 Previous Clinical Trials

3,306,317 Total Patients Enrolled

3 Trials studying Sarcopenia

263 Patients Enrolled for Sarcopenia

Michael Harris-Love, DSc MPT BSPrincipal InvestigatorRocky Mountain Regional VA Medical Center, Aurora, CO

1 Previous Clinical Trials

1 Trials studying Sarcopenia

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is enrollment currently open for this research endeavor?

"Clinicaltrials.gov reports that enrolment for this medical trial is currently closed, having been posted on March 1st 2015 and last updated February 16th 2022. However, there are 107 other clinical trials recruiting participants at present."

Answered by AI

Is the target population of this research endeavor restricted to individuals over fifty years old?

"The eligibility requirements for participation in this trial specify that, at a minimum, individuals must be 18 years old and cannot exceed 85 years of age."

Answered by AI

Does my medical background enable me to partake in this trial?

"This clinical trial demands that participants must suffer from sarcopenia and be between 18-85 years old. The research team are recruiting 136 patients in total."

Answered by AI

Recent research and studies

Frontiers in Aging NeuroscienceJournal

Quantitative Ultrasound: Measurement Considerations for the Assessment of Muscular Dystrophy and Sarcopenia

Harris-Love, Michael O., Reza Monfaredi, Catheeja Ismail, Marc R. Blackman, and Kevin Cleary. 2014. “Quantitative Ultrasound: Measurement Considerations for the Assessment of Muscular Dystrophy and Sarcopenia”. Frontiers in Aging Neuroscience. Frontiers Media SA. doi:10.3389/fnagi.2014.00172.

Frontiers in PhysiologyJournal

Disparities in the Consequences of Sarcopenia: Implications for African American Veterans

Harris-Love, Michael O., Bernadette Adams, Haniel J. Hernandez, Loretta DiPietro, and Marc R. Blackman. 2014. “Disparities in the Consequences of Sarcopenia: Implications for African American Veterans”. Frontiers in Physiology. Frontiers Media SA. doi:10.3389/fphys.2014.00250.

PeerJJournal

Ultrasound Estimates of Muscle Quality in Older Adults: Reliability and Comparison of Photoshop and Imagej for the Grayscale Analysis of Muscle Echogenicity

Harris-Love, Michael O., Bryant A. Seamon, Carla Teixeira, and Catheeja Ismail. 2016. “Ultrasound Estimates of Muscle Quality in Older Adults: Reliability and Comparison of Photoshop and Imagej for the Grayscale Analysis of Muscle Echogenicity”. Peerj. PeerJ. doi:10.7717/peerj.1721.

clinicaltrials.govStudy