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Alkylating agents

Preferred Standard Regimen for Sarcoma

N/A
Waitlist Available
Led By Edward Cheng, MD
Research Sponsored by Masonic Cancer Center, University of Minnesota
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline compared to 1 cycle and baseline to after chemotherapy
Awards & highlights

Study Summary

This trial is studying how well PET scan combined with CT scan predicts response in patients undergoing chemotherapy and surgery for soft tissue sarcoma.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~at end of each cycle
This trial's timeline: 3 weeks for screening, Varies for treatment, and at end of each cycle for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Disease-free survival
Secondary outcome measures
Compare changes in FDG-PET/CT imaging with disease-free survival by max SUV calculations
Correlate histologic response with FDG-PET/CT imaging

Trial Design

2Treatment groups
Active Control
Group I: Preferred Standard RegimenActive Control5 Interventions
Subjects with soft tissue sarcoma who are receiving pegylated liposomal doxorubicin hydrochloride, Ifosfamide with mesna and pegfilgrastim - Repeat every 28 days for 4 cycles total
Group II: Alternative Treatment RegimenActive Control5 Interventions
Subjects with soft tissue sarcoma who are receiving Doxorubicin hydrochloride, Ifosfamide with mesna and pegfilgrastim - Repeat every 28 days for 4 cycles total

Find a Location

Who is running the clinical trial?

Masonic Cancer Center, University of MinnesotaLead Sponsor
271 Previous Clinical Trials
14,555 Total Patients Enrolled
9 Trials studying Sarcoma
243 Patients Enrolled for Sarcoma
Edward Cheng, MDPrincipal InvestigatorMasonic Cancer Center, University of Minnesota
1 Previous Clinical Trials
60 Total Patients Enrolled
1 Trials studying Sarcoma
60 Patients Enrolled for Sarcoma

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
PET CT as Predictor of Response in Preoperative Chemotherapy for Soft Tissue Sarcoma
2006. "PET CT as Predictor of Response in Preoperative Chemotherapy for Soft Tissue Sarcoma". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT00346125.
~4 spots leftby Apr 2025
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