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16% O2 gas in breathed air for Healthy Subjects

N/A
Waitlist Available
Led By Dost Ongur, MD PhD
Research Sponsored by Mclean Hospital
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up during 30 minute hypoxic/hyperoxic exposure portion of themrs scan
Awards & highlights

Study Summary

This trial looks at how different oxygen levels affect the brain. People will breathe in different air mixtures, and then have an MRI scan.

Eligible Conditions
  • Healthy Subjects

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~during 30 minute hypoxic/hyperoxic exposure portion of themrs scan
This trial's timeline: 3 weeks for screening, Varies for treatment, and during 30 minute hypoxic/hyperoxic exposure portion of themrs scan for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
NAD+/NADH ratio
Secondary outcome measures
ATP
CK Kf
PCr
+1 more

Trial Design

1Treatment groups
Experimental Treatment
Group I: Healthy subjectsExperimental Treatment2 Interventions
16% O2 gas in breathed air for 30 minutes 26% O2 gas in breathed air for 30 minutes

Find a Location

Who is running the clinical trial?

Mclean HospitalLead Sponsor
212 Previous Clinical Trials
21,594 Total Patients Enrolled
Dost Ongur, MD PhDPrincipal InvestigatorMclean Hospital
3 Previous Clinical Trials
425 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does this trial have an age restriction and, if so, what is the minimum requirement for participation?

"The prerequisites for enrolment into this clinical trial necessitate that the patient is between 18 and 40 years of age. If a participant does not meet these criteria, there are 65 trials available for those under 18 and 453 studies for aged individuals over 65."

Answered by AI

Is recruitment still active for this clinical experiment?

"As per clinicaltrials.gov, this medical trial is no longer recruiting patients; the study was posted on July 1st 2023 with its most recent update occurring on July 8th 2022. However, 941 other trials are presently in search of participants."

Answered by AI

Could I potentially participate in this experiment?

"Patients who have healthy subject (hs) status and are between 18-40 years old may be accepted into this trial. There is a limit of 12 participants total for this study."

Answered by AI

Who else is applying?

What state do they live in?
Virginia
New Hampshire
How old are they?
18 - 65
What site did they apply to?
McLean Hospital
What portion of applicants met pre-screening criteria?
Met criteria
Did not meet criteria
How many prior treatments have patients received?
0

Why did patients apply to this trial?

Always looking to help science.
PatientReceived 2+ prior treatments
Recent research and studies
clinicaltrials.govStudy
Magnetic Resonance Spectroscopy Studies of Acute Hypoxic and Hyperoxic Breathing in Healthy Volunteers
Dost Ongur 2023. "Magnetic Resonance Spectroscopy Studies of Acute Hypoxic and Hyperoxic Breathing in Healthy Volunteers". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03106376.
~0 spots leftby Apr 2025
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