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Demand-driven delivery followed by free-flow delivery for Laughing Gas

N/A
Waitlist Available
Led By Carilynne Yarascavitch, BSc DDS MSc
Research Sponsored by University of Toronto
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up assessed immediately after breathing through each mechanism for 2 minutes
Awards & highlights

Study Summary

This trial will compare two methods of gas delivery in a dental setting: 1) demand-driven (DD) and 2) free-flow (FF).

Eligible Conditions
  • Laughing Gas
  • Dentistry
  • Drug Delivery System
  • Self-Care
  • Feasibility
  • Inhalation Drug Administration

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~procedure (assessed for the duration of time when the patient is breathing from either delivery system)
This trial's timeline: 3 weeks for screening, Varies for treatment, and procedure (assessed for the duration of time when the patient is breathing from either delivery system) for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Comfort of the demand-driven gas delivery mechanism
Feasibility of the demand-driven gas delivery mechanism

Trial Design

2Treatment groups
Experimental Treatment
Group I: Free-flow delivery followed by demand-driven deliveryExperimental Treatment2 Interventions
Participants will inspire 100% oxygen through their nose with the gas delivery device set to a free-flow delivery setting through a nasal hood for 2 minutes followed by inspiration of 100% oxygen through their nose with the gas delivery device set to a free-flow delivery setting through a nasal hood for 2 minutes.
Group II: Demand-driven delivery followed by free-flow deliveryExperimental Treatment2 Interventions
Participants will inspire 100% oxygen through their nose with the gas delivery device set to a demand-driven delivery setting through a nasal hood for 2 minutes followed by inspiration of 100% oxygen through their nose with the gas delivery device set to a free-flow delivery setting through a nasal hood for 2 minutes.

Find a Location

Who is running the clinical trial?

University of TorontoLead Sponsor
689 Previous Clinical Trials
1,018,543 Total Patients Enrolled
O-Two Medical TechnologiesUNKNOWN
Carilynne Yarascavitch, BSc DDS MScPrincipal InvestigatorUniversity of Toronto

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
Anesthesia ProgressJournal
Nitrous Oxide and the Inhalation Anesthetics
Becker, Daniel E., and Morton Rosenberg. 2008. “Nitrous Oxide and the Inhalation Anesthetics”. Anesthesia Progress. American Dental Society of Anesthesiology (ADSA). doi:10.2344/0003-3006-55.4.124.
Health and Quality of Life OutcomesJournal
Some Psychometric Properties of the Chinese Version of the Modified Dental Anxiety Scale with Cross Validation
Yuan, Siyang, Ruth Freeman, Satu Lahti, Ffion Lloyd-Williams, and Gerry Humphris. 2008. “Some Psychometric Properties of the Chinese Version of the Modified Dental Anxiety Scale with Cross Validation”. Health and Quality of Life Outcomes. Springer Science and Business Media LLC. doi:10.1186/1477-7525-6-22.
clinicaltrials.govStudy
Demand-Driven Method for Gas Delivery in a Dental Setting
Carilynne Yarascavitch 2020. "Demand-Driven Method for Gas Delivery in a Dental Setting". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04305990.
~20 spots leftby Apr 2025
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