Blue Light Phototherapy for Plaque Psoriasis
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial tests blue light phototherapy for treating psoriasis vulgaris and Grover's Disease. The goal is to determine if blue light can reduce symptoms on treated areas compared to untreated ones. Individuals diagnosed with psoriasis vulgaris or Grover's Disease who haven't used certain skin treatments in the past two weeks might qualify. As an unphased trial, this study provides a unique opportunity to explore new treatment possibilities for these conditions.
Will I have to stop taking my current medications?
Yes, you will need to stop taking certain medications. If you are using topical or systemic treatments for your skin condition, you must stop them at least 2 weeks before starting the trial. Also, if you are taking specific drugs like topical steroids, calcineurin inhibitors, methotrexate, retinoids, or biologic agents for other issues, you cannot participate in the trial.
What prior data suggests that Blue Light Phototherapy is safe for treating psoriasis vulgaris and Grover's Disease?
Research has shown that blue light therapy is generally safe for treating skin conditions like Grover's disease and psoriasis. In one study on Grover's disease, participants reported no side effects related to the treatment, and many preferred blue light therapy over other treatments.
For psoriasis, light therapy is effective, though mild side effects, such as slight skin irritation, may occur. Overall, patients have tolerated the treatment well. Blue light therapy uses LED lights, which are considered safe and effective in reducing skin problems. While discussing any concerns with a doctor is important, blue light therapy has a history of being a safe choice for many.12345Why are researchers excited about this trial?
Unlike standard treatments for psoriasis and Grover's disease, such as topical steroids and systemic medications, Blue Light Phototherapy offers a non-invasive approach by using specific wavelengths of blue light to target affected skin areas. This method is unique because it aims to reduce inflammation and skin lesions without the side effects often associated with traditional medications. Researchers are excited about this treatment because it could offer a safer, more targeted way to manage these skin conditions, potentially improving patient quality of life with fewer risks.
What evidence suggests that Blue Light Phototherapy might be an effective treatment for psoriasis vulgaris and Grover's Disease?
Research has shown that blue light therapy can help treat both psoriasis and Grover's Disease. In this trial, participants will receive blue light phototherapy on one affected area of their body. One study found that this therapy significantly reduced the number of skin spots and improved itching for adults with Grover's Disease, with many patients preferring it. For psoriasis, another study confirmed that blue LED light is a safe and effective option, showing noticeable improvements in the skin condition. Patients reported fewer side effects compared to other treatments. Overall, blue light therapy offers a promising alternative for managing these skin conditions.14678
Who Is on the Research Team?
Shuai Xu
Principal Investigator
Northwestern University
Are You a Good Fit for This Trial?
Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive blue light phototherapy on affected areas for psoriasis or Grover's disease
Follow-up
Participants are monitored for safety and effectiveness after treatment
Long-term follow-up
Elucidate changes in circulatory T-cells based on flow cytometry and serum cytokines with blue light therapy
What Are the Treatments Tested in This Trial?
Interventions
- Blue Light Phototherapy
Find a Clinic Near You
Who Is Running the Clinical Trial?
Northwestern University
Lead Sponsor
T-Cellerate LLC
Industry Sponsor
T-Cellerate LLC
Collaborator