Educational Video for Prostate Cancer

Overseen By Clara Hwang

Age: 18+

Sex: Male

Trial Phase: Academic

Sponsor: Henry Ford Health System

Disqualifiers: Prior germline testing, Positive somatic test

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: 1

50 Participants Needed

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to increase genetic testing rates for black patients with aggressive prostate cancer. Participants will watch an educational video about genetic testing and may undergo a genetic test to learn more about their cancer risk. The trial seeks black men with prostate cancer who have a family history of cancer or high-risk prostate cancer. Participants will answer questions before and after the session to assess how the video affects their understanding and decision-making about genetic testing. As an unphased study, this trial offers an opportunity to contribute to research that could enhance genetic testing awareness and decision-making for future patients.

Will I have to stop taking my current medications?

The trial information does not specify whether you need to stop taking your current medications. It seems focused on educational sessions and genetic testing, so it's unlikely that your medications will be affected.

What prior data suggests that this educational video is safe?

Research has shown that educational videos about prostate cancer are safe and helpful. Studies have found that these videos can increase knowledge and reduce uncertainty about cancer screening. For example, one study discovered that watching a video helped people understand prostate cancer better and feel more confident about getting screened.

Another study compared different methods of teaching men about prostate cancer and found that videos were as effective as online methods. This indicates that videos are a reliable way to share information.

Overall, educational videos are well-received and have no reported negative effects. They aim to inform and help people feel more comfortable with their healthcare choices. ^{1 2 3 4 5}

Why are researchers excited about this trial?

Researchers are excited about this trial because it explores how an educational video can enhance understanding of genetic testing for prostate cancer. Unlike standard treatments that focus on directly treating the cancer, this approach aims to empower patients with vital knowledge, potentially leading to more informed decisions about their health. This method is unique because it emphasizes education as a tool for patient engagement and decision-making, which could complement existing treatment options by helping patients navigate their choices more effectively.

What evidence suggests that this educational video is effective for improving germline genetic testing rates in prostate cancer?

Research has shown that educational videos can greatly enhance understanding of genetic testing. One study found that videos significantly improved patients' knowledge about prostate cancer screening and treatment. Another study indicated that these videos serve as a good alternative to traditional genetic counseling for various cancers, including prostate cancer. They help patients grasp the benefits, risks, and limitations of genetic tests. In this trial, participants will receive an educational intervention involving a video to support informed decision-making about genetic testing for prostate cancer. Evidence suggests that using an educational video effectively aids patients in making informed decisions about genetic testing for prostate cancer. ^{3 6 7 8 9}

Are You a Good Fit for This Trial?

This trial is for black or multiracial men including black, aged 18+, with high-risk prostate cancer. They should meet NCCN guidelines for germline testing and have a significant family history of certain cancers or a diagnosis of aggressive prostate cancer regardless of family history. Men who've already had genetic testing are excluded.

Inclusion Criteria

I am a man with low to intermediate risk prostate cancer and have a significant family history of cancer.

I am a man aged 18 or older.

I am a man with high-risk or very high-risk prostate cancer, including if it has spread to lymph nodes or is metastatic.

Exclusion Criteria

I have undergone genetic testing.

My genetic test shows a possible inherited variant.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Educational Intervention

Participants undergo a one-on-one in-person education session regarding germline testing in prostate cancer, including pre- and post-intervention questionnaires.

1 day

1 visit (in-person)

Genetic Testing

Participants who agree to proceed with testing will undergo germline cancer genetic testing via a commercial lab test.

Varies

Follow-up

Participants are monitored for the impact of genetic testing results on clinical management, including clinician surveys.

24 months

What Are the Treatments Tested in This Trial?

Interventions

• Educational video

Trial Overview The study tests whether an educational video can increase the completion rates of recommended genetic testing in black patients with high-risk prostate cancer. Participants will watch an educational session and may then undergo genetic testing.

How Is the Trial Designed?

Group I: Educational intervention Experimental Treatment 1 Intervention

Patients will be asked questions about genetic testing for prostate cancer before and after an educational intervention.

Who Is Running the Clinical Trial?

Henry Ford Health System

Lead Sponsor

Trials

334

Recruited

2,197,000+

Published Research Related to This Trial

In a study of 2550 men with localized prostate cancer, radical prostatectomy led to a greater decline in sexual function and increased urinary incontinence compared to external beam radiation therapy (EBRT) and active surveillance after 3 years.

While radical prostatectomy resulted in worse urinary incontinence, it was associated with fewer urinary irritative symptoms compared to active surveillance, indicating that treatment choice can significantly impact quality of life outcomes.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Association Between Radiation Therapy, Surgery, or Observation for Localized Prostate Cancer and Patient-Reported Outcomes After 3 Years. Barocas, DA., Alvarez, J., Resnick, MJ., et al.[2022]

There is an increasing focus on the psychosocial challenges faced by prostate cancer patients, highlighting the need for educational and group interventions to address these issues.

Research has identified various unmet needs among prostate cancer patients, including information and support related to diagnosis, treatment, and quality of life, indicating significant areas for improvement in patient care.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Psychosocial and educational aspects in prostate cancer patients. Visser, A., van Andel, G.[2019]

Physicians found multimedia-supported education for preoperative patient education in radical prostatectomy to be superior to standard methods, citing better comprehensibility and easier explanation of complex topics, despite no actual difference in time taken for education.

All participating physicians preferred multimedia support for patient education, indicating a strong willingness to adopt this method in clinical practice, which could enhance patient understanding and satisfaction.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Multimedia support in preoperative patient education for radical prostatectomy: the physicians' point of view. Ihrig, A., Herzog, W., Huber, CG., et al.[2019]

A video intervention significantly increased knowledge about prostate cancer screening and treatment among 52 patients in the experimental group, compared to no change in the control group, indicating its effectiveness as an educational tool.

The video also influenced patients' preferences for prostate-specific antigen (PSA) screening, with 31% of the experimental group changing their preference compared to only 2% in the control group, demonstrating its impact on patient decision-making without causing confusion or fear.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Efficacy of a video for teaching patients about prostate cancer screening and treatment. Ruthman, JL., Ferrans, CE.[2018]

A review of educational intervention trials in prostate cancer over the last 10 years revealed that most studies focused on managing the disease, treatments, and side effects, highlighting the importance of education in patient care.

Understanding psychosocial stressors and educational interventions is essential for nurses, as these factors significantly impact the well-being of men with prostate cancer and their families.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Psychosocial and educational intervention trials in prostate cancer. Germino, BB.[2019]

A total of 226 YouTube videos related to laparoscopic and robotic radical prostatectomy were analyzed, revealing that robotic/robot-assisted videos were longer and had a higher PACE score for the urethro-vesical anastomosis step compared to laparoscopic videos.

Despite the presence of high-quality educational content on YouTube, there is currently no objective measure to consistently predict the educational quality of these surgical videos.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Does YouTube include high-quality resources for training on laparoscopic and robotic radical prostatectomy? Arslan, B., Gönültaş, S., Gökmen, E., et al.[2021]

In a study of 2005 men with localized prostate cancer, those who underwent nerve-sparing prostatectomy reported significantly worse urinary incontinence and sexual function compared to those who chose active surveillance, highlighting the potential adverse effects of surgical treatment.

For men with unfavorable-risk prostate cancer, while prostatectomy led to worse sexual function over 5 years, those treated with external beam radiation therapy (EBRT) combined with androgen deprivation therapy (ADT) experienced better sexual function and less incontinence, suggesting that treatment choice can significantly impact long-term quality of life.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Patient-Reported Outcomes Through 5 Years for Active Surveillance, Surgery, Brachytherapy, or External Beam Radiation With or Without Androgen Deprivation Therapy for Localized Prostate Cancer. Hoffman, KE., Penson, DF., Zhao, Z., et al.[2022]

Patients with low socioeconomic status and/or low literacy face significant challenges in managing prostate cancer, highlighting the need for targeted educational programs to improve their understanding and treatment outcomes.

Involving practice nurses and health educators can enhance patient engagement in treatment decisions and improve posttreatment follow-up, leading to better management of complications and earlier diagnosis.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Managing the low-socioeconomic-status prostate cancer patient. Rayford, W.[2021]

The introduction of video-based educational resources for patients undergoing robotic prostatectomy led to a significant reduction in delayed discharges, with a decrease from 64% to 55% in late discharges post-intervention (p<0.05).

Patient satisfaction remained high and unchanged between the intervention and non-intervention groups, indicating that the use of videos did not negatively impact the patient experience.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Use of video education in postoperative patient counselling: A quality improvement initiative. Witherspoon, LDE., Gan, AML., Breau, RH., et al.[2022]

The Prostate Interactive Educational System (PIES) was well accepted by 72 patients with newly diagnosed localized prostate cancer, enhancing their treatment decision-making process without disrupting clinical routines.

Patients using PIES reported greater confidence in their treatment choices, found the information more helpful and reassuring, and experienced less anxiety compared to those receiving standard information, indicating that PIES effectively supports patients in navigating their treatment options.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Acceptability and preliminary feasibility of an internet/CD-ROM-based education and decision program for early-stage prostate cancer patients: randomized pilot study. Diefenbach, MA., Mohamed, NE., Butz, BP., et al.[2021]

A study analyzing 100 YouTube videos on prostate cancer revealed that these videos were viewed over 50 million times, highlighting the platform's significant role in disseminating health information.

Most videos aimed to provide information about prostate cancer, with a notable difference in credibility: videos from medical professionals and government sources were more likely to be informative compared to those from consumers or commercial sources.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

A Content Analysis of YouTube™ Videos Related to Prostate Cancer. Basch, CH., Menafro, A., Mongiovi, J., et al.[2019]

Citations

1. ascopubs.org ascopubs.org/doi/10.1200/OP-24-00809

Results From a Randomized Study | JCO Oncology Practice Video Education Is an Acceptable Alternative to Pretest Genetic Counseling for Patients With Breast, Ovarian, Pancreatic, and Metastatic ...

2. clinicaltrials.gov clinicaltrials.gov/study/NCT06166758

Feasibility Study: Educational Genetic Test Video Assess the value of presenting patients an educational video regarding the benefits risks, and limitations of genetic testing for hereditary cancer risk.

3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov/articles/PMC12275682/

Educational videos in genetic counseling: Meeting patients ... This study examined the effects of self-developed educational videos on patient satisfaction and the physician-patient relationship in genetic outpatient ...

4. withpower.com withpower.com/trial/phase-prostatic-neoplasms-9-2023-98a6a

Educational Video for Prostate Cancer A video intervention significantly increased knowledge about prostate cancer screening and treatment among 52 patients in the experimental group, compared to no ...

5. asco.org asco.org/abstracts-presentations/ABSTRACT298813

A randomized controlled trial of video-education or in- ... A randomized controlled trial of video-education or in-person genetic counseling for men with prostate cancer (ProGen). download. Background: Approximately 10% ...

6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov/articles/PMC7445972/

Prostate Cancer-based Interventions' Efficacy on ... The results indicated that the video and booklet significantly improved the level of knowledge and lessened decisional conflict in the experimental group, ...

7. bjui-journals.onlinelibrary.wiley.com bjui-journals.onlinelibrary.wiley.com/doi/10.1002/bco2.200

Accuracy of prostate cancer screening recommendations for ... This study aimed to evaluate content quality and racial/ethnic representation, particularly of high-risk cohorts, of prostate cancer screening videos on ...

8. news-medical.net news-medical.net/news/20240410/Educational-video-boosts-prostate-cancer-screening-intentions-in-men.aspx

Educational video boosts prostate cancer screening ... The video increased knowledge about prostate cancer and screening, and reduced uncertainty about obtaining prostate cancer screening in a diverse group of more ...

9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov/articles/PMC1494924/

A Randomized Controlled Trial Comparing Internet and Video ... This study compared internet and video patient education modalities for men considering the prostate specific antigen (PSA) test.