Educational Video for Prostate Cancer

Overseen By Clara Hwang

Age: 18+

Sex: Male

Trial Phase: Academic

Sponsor: Henry Ford Health System

Disqualifiers: Prior germline testing, Positive somatic test

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: 1

50 Participants Needed

Trial Summary

What is the purpose of this trial?

This is a pilot study to improve rates of germline genetic testing for black patients with aggressive prostate cancer as recommended by the updated guidelines by the National Cancer Comprehensive Network (NCCN) in 2018. In this study, consented patients will undergo a low-risk intervention of an educational session with a trained staff member on germline testing in prostate cancer and, if agreeable, subsequent germline cancer genetic testing via a commercial lab test.

Will I have to stop taking my current medications?

The trial information does not specify whether you need to stop taking your current medications. It seems focused on educational sessions and genetic testing, so it's unlikely that your medications will be affected.

What data supports the effectiveness of the treatment Educational video for prostate cancer?

Research shows that educational videos can help patients understand prostate cancer screening and treatment, improve their participation in decision-making, and manage post-treatment complications effectively. Additionally, video education has been found to maintain high patient satisfaction and potentially reduce hospital discharge delays after surgery. ^{1 2 3 4 5}

Is the educational video for prostate cancer safe for humans?

The educational video for prostate cancer is designed to help patients understand their treatment options and does not involve any physical treatment or medication, so it is generally safe for humans. ^{1 6 7 8 9}

How does the educational video treatment for prostate cancer differ from other treatments?

The educational video treatment is unique because it focuses on providing patients with information about prostate cancer and its treatment options through an engaging and accessible format, helping them make informed decisions. Unlike traditional medical treatments, this approach emphasizes patient education and involvement in the decision-making process. ^{1 6 8 10 11}

Eligibility Criteria

This trial is for black or multiracial men including black, aged 18+, with high-risk prostate cancer. They should meet NCCN guidelines for germline testing and have a significant family history of certain cancers or a diagnosis of aggressive prostate cancer regardless of family history. Men who've already had genetic testing are excluded.

Inclusion Criteria

I am a man with low to intermediate risk prostate cancer and have a significant family history of cancer.

I am a man aged 18 or older.

I am a man with high-risk or very high-risk prostate cancer, including if it has spread to lymph nodes or is metastatic.

Exclusion Criteria

I have undergone genetic testing.

My genetic test shows a possible inherited variant.

Timeline

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Educational Intervention

Participants undergo a one-on-one in-person education session regarding germline testing in prostate cancer, including pre- and post-intervention questionnaires.

1 day

1 visit (in-person)

Genetic Testing

Participants who agree to proceed with testing will undergo germline cancer genetic testing via a commercial lab test.

Varies

Follow-up

Participants are monitored for the impact of genetic testing results on clinical management, including clinician surveys.

24 months

Treatment Details

Interventions

• Educational video

Trial Overview The study tests whether an educational video can increase the completion rates of recommended genetic testing in black patients with high-risk prostate cancer. Participants will watch an educational session and may then undergo genetic testing.

Participant Groups

Group I: Educational intervention Experimental Treatment 1 Intervention

Patients will be asked questions about genetic testing for prostate cancer before and after an educational intervention.

Who Is Running the Clinical Trial?

Henry Ford Health System

Lead Sponsor

Trials

334

Recruited

2,197,000+

Findings from Research

A video intervention significantly increased knowledge about prostate cancer screening and treatment among 52 patients in the experimental group, compared to no change in the control group, indicating its effectiveness as an educational tool.

The video also influenced patients' preferences for prostate-specific antigen (PSA) screening, with 31% of the experimental group changing their preference compared to only 2% in the control group, demonstrating its impact on patient decision-making without causing confusion or fear.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Efficacy of a video for teaching patients about prostate cancer screening and treatment. Ruthman, JL., Ferrans, CE.[2018]

Patients with low socioeconomic status and/or low literacy face significant challenges in managing prostate cancer, highlighting the need for targeted educational programs to improve their understanding and treatment outcomes.

Involving practice nurses and health educators can enhance patient engagement in treatment decisions and improve posttreatment follow-up, leading to better management of complications and earlier diagnosis.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Managing the low-socioeconomic-status prostate cancer patient. Rayford, W.[2021]

There is an increasing focus on the psychosocial challenges faced by prostate cancer patients, highlighting the need for educational and group interventions to address these issues.

Research has identified various unmet needs among prostate cancer patients, including information and support related to diagnosis, treatment, and quality of life, indicating significant areas for improvement in patient care.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Psychosocial and educational aspects in prostate cancer patients. Visser, A., van Andel, G.[2019]

Physicians found multimedia-supported education for preoperative patient education in radical prostatectomy to be superior to standard methods, citing better comprehensibility and easier explanation of complex topics, despite no actual difference in time taken for education.

All participating physicians preferred multimedia support for patient education, indicating a strong willingness to adopt this method in clinical practice, which could enhance patient understanding and satisfaction.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Multimedia support in preoperative patient education for radical prostatectomy: the physicians' point of view. Ihrig, A., Herzog, W., Huber, CG., et al.[2019]

The introduction of video-based educational resources for patients undergoing robotic prostatectomy led to a significant reduction in delayed discharges, with a decrease from 64% to 55% in late discharges post-intervention (p<0.05).

Patient satisfaction remained high and unchanged between the intervention and non-intervention groups, indicating that the use of videos did not negatively impact the patient experience.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Use of video education in postoperative patient counselling: A quality improvement initiative. Witherspoon, LDE., Gan, AML., Breau, RH., et al.[2022]

The Prostate Interactive Educational System (PIES) was well accepted by 72 patients with newly diagnosed localized prostate cancer, enhancing their treatment decision-making process without disrupting clinical routines.

Patients using PIES reported greater confidence in their treatment choices, found the information more helpful and reassuring, and experienced less anxiety compared to those receiving standard information, indicating that PIES effectively supports patients in navigating their treatment options.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Acceptability and preliminary feasibility of an internet/CD-ROM-based education and decision program for early-stage prostate cancer patients: randomized pilot study. Diefenbach, MA., Mohamed, NE., Butz, BP., et al.[2021]

In a study of 2005 men with localized prostate cancer, those who underwent nerve-sparing prostatectomy reported significantly worse urinary incontinence and sexual function compared to those who chose active surveillance, highlighting the potential adverse effects of surgical treatment.

For men with unfavorable-risk prostate cancer, while prostatectomy led to worse sexual function over 5 years, those treated with external beam radiation therapy (EBRT) combined with androgen deprivation therapy (ADT) experienced better sexual function and less incontinence, suggesting that treatment choice can significantly impact long-term quality of life.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Patient-Reported Outcomes Through 5 Years for Active Surveillance, Surgery, Brachytherapy, or External Beam Radiation With or Without Androgen Deprivation Therapy for Localized Prostate Cancer. Hoffman, KE., Penson, DF., Zhao, Z., et al.[2022]

A total of 226 YouTube videos related to laparoscopic and robotic radical prostatectomy were analyzed, revealing that robotic/robot-assisted videos were longer and had a higher PACE score for the urethro-vesical anastomosis step compared to laparoscopic videos.

Despite the presence of high-quality educational content on YouTube, there is currently no objective measure to consistently predict the educational quality of these surgical videos.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Does YouTube include high-quality resources for training on laparoscopic and robotic radical prostatectomy? Arslan, B., Gönültaş, S., Gökmen, E., et al.[2021]

In a study of 2550 men with localized prostate cancer, radical prostatectomy led to a greater decline in sexual function and increased urinary incontinence compared to external beam radiation therapy (EBRT) and active surveillance after 3 years.

While radical prostatectomy resulted in worse urinary incontinence, it was associated with fewer urinary irritative symptoms compared to active surveillance, indicating that treatment choice can significantly impact quality of life outcomes.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Association Between Radiation Therapy, Surgery, or Observation for Localized Prostate Cancer and Patient-Reported Outcomes After 3 Years. Barocas, DA., Alvarez, J., Resnick, MJ., et al.[2022]

A review of educational intervention trials in prostate cancer over the last 10 years revealed that most studies focused on managing the disease, treatments, and side effects, highlighting the importance of education in patient care.

Understanding psychosocial stressors and educational interventions is essential for nurses, as these factors significantly impact the well-being of men with prostate cancer and their families.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Psychosocial and educational intervention trials in prostate cancer. Germino, BB.[2019]

A study analyzing 100 YouTube videos on prostate cancer revealed that these videos were viewed over 50 million times, highlighting the platform's significant role in disseminating health information.

Most videos aimed to provide information about prostate cancer, with a notable difference in credibility: videos from medical professionals and government sources were more likely to be informative compared to those from consumers or commercial sources.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

A Content Analysis of YouTube™ Videos Related to Prostate Cancer. Basch, CH., Menafro, A., Mongiovi, J., et al.[2019]

References

1. United States pubmed.ncbi.nlm.nih.gov

Efficacy of a video for teaching patients about prostate cancer screening and treatment. [2018]

2. United States pubmed.ncbi.nlm.nih.gov

Managing the low-socioeconomic-status prostate cancer patient. [2021]

3. Ireland pubmed.ncbi.nlm.nih.gov

Psychosocial and educational aspects in prostate cancer patients. [2019]

4. Ireland pubmed.ncbi.nlm.nih.gov

Multimedia support in preoperative patient education for radical prostatectomy: the physicians' point of view. [2019]

5. Canada pubmed.ncbi.nlm.nih.gov

Use of video education in postoperative patient counselling: A quality improvement initiative. [2022]

6. Canada pubmed.ncbi.nlm.nih.gov

Acceptability and preliminary feasibility of an internet/CD-ROM-based education and decision program for early-stage prostate cancer patients: randomized pilot study. [2021]

7. United States pubmed.ncbi.nlm.nih.gov

Patient-Reported Outcomes Through 5 Years for Active Surveillance, Surgery, Brachytherapy, or External Beam Radiation With or Without Androgen Deprivation Therapy for Localized Prostate Cancer. [2022]

8. Germany pubmed.ncbi.nlm.nih.gov

Does YouTube include high-quality resources for training on laparoscopic and robotic radical prostatectomy? [2021]

9. United States pubmed.ncbi.nlm.nih.gov

Association Between Radiation Therapy, Surgery, or Observation for Localized Prostate Cancer and Patient-Reported Outcomes After 3 Years. [2022]

10. United States pubmed.ncbi.nlm.nih.gov

Psychosocial and educational intervention trials in prostate cancer. [2019]

11. United States pubmed.ncbi.nlm.nih.gov

A Content Analysis of YouTube™ Videos Related to Prostate Cancer. [2019]