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LDR Brachytherapy for Prostate Cancer (PRIAPUS Trial)
PRIAPUS Trial Summary
This trial is testing a new, MR-guided 3D ultrasound technique to see if it can more effectively treat prostate cancer while sparing the surrounding nerves and vessels.
PRIAPUS Trial Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowPRIAPUS Trial Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.PRIAPUS Trial Design
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Who is running the clinical trial?
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- My prostate cancer is at an intermediate or high risk level.My prostate cancer is confined to one lobe, or a recent scan shows a major lesion there.My prostate cancer was confirmed by a biopsy.I have no health issues preventing prostate seed implant therapy.You are unable to undergo an MRI scan due to certain medical conditions.My prostate cancer is considered low or favorable intermediate risk.My prostate cancer is present in both lobes without aggressive features on MRI.I have had radiation therapy to my pelvis before.I am using medication to reduce prostate size.My MRI shows cancer spread beyond the prostate capsule or to the seminal vesicles.My MRI shows signs of cancer in both lobes of my prostate.I cannot undergo general or spinal anesthesia due to health reasons.My cancer has spread to distant parts of my body and/or lymph nodes.I am over 75 years old.I have had a prostate surgery known as TURP.I have had surgery to remove the rectum and anus.I am sexually active.I have inflammatory bowel disease.
- Group 1: Prostate Cancer Patients
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Are there any available vacancies for individuals to join the trial?
"Affirmative. Information on clinicaltrials.gov suggests that this research is actively recruiting volunteers, with the original post dating back to June 1st 2021 and a recent update of May 16th 2022. This trial requires 10 participants from just one medical centre."
Are participants aged over 80 being recruited for this research?
"This clinical trial is targeting patients that are between 18 to 75 years in age. Underage individuals may take part in the 76 trials available, while elderly persons can join one of 1,315 studies designed for them."
What is the size of the patient cohort participating in this experiment?
"Affirmative. According to the clinicaltrials.gov database, this medical trial is presently enrolling participants and has been since June 1st 2021. The most recent update was on May 16th 2022 and 10 individuals are required from one site for successful recruitment."
Who would be the ideal candidates for participating in this clinical investigation?
"This medical trial is seeking 10 persons between 18 and 75 years of age who have been diagnosed with prostate cancer. Furthermore, patients must satisfy the following criteria: as classified by National Comprehensive Cancer Network (NCCN), having a low- or favourable intermediate risk; no known contraindications to LDR brachytherapy; minimal erectile dysfunction (a score above 18 in International Index of Erectile Function- 5 [IIEF-5] without PDE-5 inhibitor assistance); biopsy verified adenocarcinoma of the prostate; all pathological cores limited to one lobe unless recent MRI scan (< 6 months from enrollment"
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