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Imaging

Micro-Ultrasound Imaging for Prostate Cancer (MUSIC-AS Trial)

N/A

Recruiting

Research Sponsored by University of Alberta

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up immediately after biopsy.

Awards & highlights

MUSIC-AS Trial Summary

This trial will compare two imaging tests to measure prostate cancer progression and collect blood samples for future research.

Who is the study for?

This trial is for adult men with low-grade prostate cancer (Gleason Grade Group 1) who are being monitored closely rather than receiving immediate treatment and need a confirmatory biopsy. Participants must be able to undergo both a prostate biopsy and an MRI.Check my eligibility

What is being tested?

The study is testing if high-resolution micro-ultrasound imaging is as good as MRI in detecting significant changes in prostate cancer during active surveillance. It involves taking targeted samples using micro-ultrasound, then MRI, followed by systematic biopsies.See study design

What are the potential side effects?

While the trial itself focuses on imaging techniques that do not have side effects like drugs, undergoing biopsies can lead to discomfort, bleeding, infection risk or temporary difficulty urinating.

MUSIC-AS Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ immediately after biopsy.

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~immediately after biopsy.

This trial's timeline: 3 weeks for screening, Varies for treatment, and immediately after biopsy. for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Magnetic Resonance Imaging

Secondary outcome measures

Cancer upgrading during Active surveillance between imagine-guided versus systematic biopsy.

MUSIC-AS Trial Design

1Treatment groups

Experimental Treatment

Group I: Combined MRI and micro-ultrasound guided prostate biopsy.Experimental Treatment1 Intervention

In a single biopsy session, first, a microUS-guided biopsy of regions of interest (ROIs) will be performed. The MRI fusion software will then be turned on, the clinician unblinded to the MRI results, and biopsy cores from within the boundaries of the MRI-fused lesion will be sampled from ROIs. Up to two ROIs identified on microUS or MRI will be targeted with up to 3 cores per ROI. If the MRI ROIs overlap with the microUS ROIs after unblinding, then the cores taken during the microUS-guided biopsy will be counted as both microUS and MRI-guided. Finally, a standard 12-core systematic biopsy will be performed.

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

University of AlbertaLead Sponsor

889 Previous Clinical Trials

384,924 Total Patients Enrolled

9 Trials studying Prostate Cancer

5,344 Patients Enrolled for Prostate Cancer

Media Library

High-resolution micro-ultrasound (Imaging) Clinical Trial Eligibility Overview. Trial Name: NCT05558241 — N/A

Prostate Cancer Research Study Groups: Combined MRI and micro-ultrasound guided prostate biopsy.

Prostate Cancer Clinical Trial 2023: High-resolution micro-ultrasound Highlights & Side Effects. Trial Name: NCT05558241 — N/A

High-resolution micro-ultrasound (Imaging) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05558241 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there any vacancies remaining for individuals interested in participating in this clinical trial?

"As evidenced by clinicaltrials.gov, this study is currently recruiting patients. The trial was first advertised on January 1st 2023 and has been revised most recently on the 12th of January 2023."

Answered by AI

How many participants are allowed to join this experiment?

"Affirmative. The information available on clinicaltrials.gov confirms that this experiment is actively searching for participants and was published on January 1st 2023, with the last update being made on December 12th of the same year. 210 volunteers need to be recruited from a single site."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Micro-UltraSound In Cancer - Active Surveillance

2023. "Micro-UltraSound In Cancer - Active Surveillance". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05558241.