Imaging Panel for Prostate Cancer

Phase-Based Progress Estimates
London Health Sciences Centre, London, Canada
Prostate Cancer+1 More
Imaging Panel - Other
Eligible conditions

Study Summary

Multi-modality Prostate Cancer Image Guided Interventions

See full description

Eligible Conditions

  • Prostate Cancer

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

This trial is evaluating whether Imaging Panel will improve 1 primary outcome and 1 other outcome in patients with Prostate Cancer. Measurement will happen over the course of Within two years of study completion..

Within two years of study completion
MRI Prostate Sodium Imaging Validation
Within two years of study completion.
Hybrid Imaging Map (HIM) Validation

Trial Safety

Safety Progress

1 of 3

Trial Design

1 Treatment Group

Imaging Panel
1 of 1
Experimental Treatment

This trial requires 52 total participants across 1 different treatment group

This trial involves a single treatment. Imaging Panel is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.

Imaging Panel
Patients who provided written informed consent and found to be eligible for study were asked to complete Positron Emission Tomography (PET) + Dynamic CT imaging, PET/MRI (with endorectal coil) and 3D-Transrectal ultrasound prior to standard of care radical prostatectomy.

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: within two years of study completion
This trial has the following approximate timeline: 3 weeks for initial screening, variable treatment timelines, and roughly within two years of study completion for reporting.

Closest Location

London Health Sciences Centre - London, Canada

Eligibility Criteria

This trial is for male patients aged 18 and older. There are 4 eligibility criteria to participate in this trial as listed below.

Mark “yes” if the following statements are true for you:
Pathologically confirmed prostate cancer on previous biopsy
Suitable for and consenting to Radical Prostatectomy for treatment, or repeat biopsy as standard of care
Provision of informed consent for this study
Male, aged 18 years or older

Patient Q&A Section

What are the signs of prostate cancer?

"Men with [prostate cancer]( are usually overactive and have lower sex hormone levels than men without prostate cancer. As sex hormone levels fall with age, symptoms and signs of prostate cancer tend to fade. The most common signs, however, are persistent back pain, unexplained bleeding and enlargement of the prostate gland. Diagnosis of prostate cancer is often not evident until the disease has had a long period of latency. This is why some signs, such as unexplained bleeding and back pain, do not occur at the right time for diagnosis and treatment. Once treatment starts, the body's natural hormonal state starts to shift to match what is expected from cancer treatment." - Anonymous Online Contributor

Unverified Answer

Can prostate cancer be cured?

"There is no evidence that prostate cancer is curable. Even when complete clinical remission is obtained, these cases still frequently recur. Therefore, cure is inappropriate as the goal of treatment, and therapeutic intervention may only be appropriate for a period of time after a recurrent disease." - Anonymous Online Contributor

Unverified Answer

How many people get prostate cancer a year in the United States?

"This US study shows a prevalence of 0.8 per 1000 men over a wide age range for prostate cancer. The prevalence of prostate cancer increases with age, the higher it is over age 60 is around 1.5 per 1000 men. In men ages 45 to 75, the prevalence of prostate cancer increases linearly with advancing age. These men are most likely to be informed of their diagnosis and should have early and continuous surveillance for clinically significant disease. Prostate cancer is uncommon among African American men aged 20-60 years which is similar to what is reported in other US studies. These men, and men of their spouses are most likely to be tested for prostate cancer in clinics or by their physician." - Anonymous Online Contributor

Unverified Answer

What are common treatments for prostate cancer?

"If [prostate cancer]( is diagnosed by an early age when treatment is available, radical prostatectomy or radiation therapy may be recommended. Prostate cancer is also highly chemo-sensitive so chemotherapy may be prescribed even when an early detection test is negative. However, only 6% of prostate cancer patients would receive adjuvant treatment." - Anonymous Online Contributor

Unverified Answer

What causes prostate cancer?

"The correlation between prostate cancer and other diseases and its cause are a subject of debate. Data from a recent study from this study are in accordance with the findings reported from previous reports. They support that prostate cancer in the present study is correlated to diseases, lifestyle and psychological factors. Moreover, genetic, nutritional or environmental factors play significant role in its causation." - Anonymous Online Contributor

Unverified Answer

What is prostate cancer?

"The word "cancer" implies that a disease is terminal, that it has few and serious treatments, has an adverse prognosis, and is invariably fatal. On the other hand, cancer is one of the more prevalent diseases and is the reason that almost one million people die each year in the US. Thus, what is cancer? If we answer that question, we start to understand and treat this disease better." - Anonymous Online Contributor

Unverified Answer

How serious can prostate cancer be?

"Prostate cancer patients with very high grade and stage (and most commonly those with very few lymph nodes with cancers) are very rarely likely to benefit from any treatment other than palliative care. Prostate-specific antigen values above 20 ng/mL in the presence of clinically detectable disease are indicative of a poor prognosis that usually necessitates curative treatment." - Anonymous Online Contributor

Unverified Answer

Is imaging panel typically used in combination with any other treatments?

"The high proportionality and the number of the scans used in combination with the treatments for each patient justifies our choice of the Imaging Panel for patients treated with radiotherapy alone or radiotherapy combined with surgery plus adjuvant radiotherapy." - Anonymous Online Contributor

Unverified Answer

Does imaging panel improve quality of life for those with prostate cancer?

"For those who are eligible for image-guided radiation therapy (IGRT), there were no differences in treatment plan dose volumes for prostate cancer patients based on imaging panel type or dosimetric data provided; however, there was a significant increase in treatment time for those treated with the IGRT panel." - Anonymous Online Contributor

Unverified Answer

What is the average age someone gets prostate cancer?

"A national study indicates that prostate cancer often presents at a younger age in the United States than has been estimated on the basis of autopsy studies, indicating that prostate cancer onset may be age dependent. This finding may have important ramifications for public health, as treatment options at younger ages may result in more effective therapeutic strategies than is the case for older men." - Anonymous Online Contributor

Unverified Answer

Does prostate cancer run in families?

"A large number of prostate cancers occur in families with a hereditary background. Data from a recent study suggest screening for prostate cancer may provide a useful tool for preventing premature death from this disease." - Anonymous Online Contributor

Unverified Answer

How does imaging panel work?

"• This first study to illustrate the unique ways in which these common clinical scenarios are addressed in the radiology population supports the potential role of imaging as a key component of patient management of benign prostatic pathologies, of clinical complexity or difficulty." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
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