AI-Generated Health Messages for Outpatient Care

(AI-CARE Trial)

Age: 18+

Sex: Any

Trial Phase: Academic

Sponsor: Hopital Montfort

Disqualifiers: Illiteracy, No email, No device, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: Unknown

50 Participants Needed

Trial Summary

What is the purpose of this trial?

This study investigates the use of Generative AI (GAI) to support primary care practices in delivering accurate, accessible patient education. With the rise of health misinformation, increasingly complex patient needs, and a strained healthcare workforce, primary care must find new ways to communicate trusted health information effectively. Leveraging the Canadian Primary Care Information Network (CPIN), this study will generate patient education messages on key health topics using both GAI and human content experts. Diverse review panels of patients and providers will assess the messages on quality of information, adaptability, and relevance and usefulness, with special attention to socioeconomic factors that may impact message accessibility. CPIN will recruit a diverse sample of participants to evaluate both GAI- and human-generated messages. Review panels will provide structured feedback via surveys, aiming to identify differences in content quality and effectiveness. The study's goal is to determine whether GAI can produce high-quality health information that meets primary care standards. Results will reveal how GAI tools can support primary care in reducing misinformation and administrative burdens, fostering patient-provider relationships, and improving health equity. Findings will inform best practices for integrating GAI in primary care to ensure accessible, timely patient education across Canada.

Research Team

William Hogg, MD, MSc

Principal Investigator

Institut du Savoir Montfort

Sharon Johnston, MD, LLM

Principal Investigator

Institut du Savoir Montfort

Eligibility Criteria

This trial is for individuals who can visit outpatient clinics and are interested in evaluating health promotional messages. Participants will be involved in reviewing the quality of information provided by both AI-generated and human-created health messages.

Inclusion Criteria

Providers' review panel must be diverse primary care providers providing comprehensive care in Canada. They must be proficient in either written English or French and able to consent to participate in the study.

I am skilled in primary care, public health, or health communication and speak French natively.

I am 18 or older, can understand English or French, and can consent to join the study.

Exclusion Criteria

I am unable to give informed consent myself due to age or condition.

Content team members, primary care providers, or patients who cannot write (content team members) or read (review panels) in either French or English.

Primary care providers or patients who do not have an email address, a computer, or a cellphone to complete the evaluations on REDCap.

Timeline

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Content Generation and Evaluation

Generative AI and human experts create patient education messages. Review panels assess the messages on quality, adaptability, and relevance.

12 months

Monthly evaluations

Follow-up

Participants are monitored for feedback on message effectiveness and quality

4 weeks

Treatment Details

Interventions

• Health promotional messages generated by Artificial Intelligence

Trial Overview The study compares patient education materials generated by Generative AI with those created by human experts. It aims to assess their quality, adaptability, relevance, and usefulness through feedback from diverse panels of patients and providers.

Participant Groups

Group I: Artificial Intelligence Experimental Treatment 1 Intervention

Group II: Human expert Active Control 1 Intervention

Who Is Running the Clinical Trial?

Hopital Montfort

Lead Sponsor

Trials

15

Recruited

5,000+

Cheo Research Institute

Collaborator

CHEO Research Institute

Collaborator

Trials

3

Recruited

1,100+

Eastern Ontario Health Unit

Collaborator

Trials

1

Recruited

10+