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Patients with PVCs for Myocarditis

N/A
Recruiting
Led By Dhanunjaya Lakkireddy, MD
Research Sponsored by Kansas City Heart Rhythm Research Foundation
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 12 months
Awards & highlights

Study Summary

This prospective, observational study is a single center clinical registry of patients referred for management of symptomatic or asymptomatic Premature Ventricular Contractions (PVCs). Subjects will be followed through 12 months. The study will enroll approximately 50 patients.

Eligible Conditions
  • Premature Ventricular Contractions
  • Myocarditis

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~12 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and 12 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Associated atrial and ventricular arrhythmias
Evaluation of efficacy of immunosuppressive therapy - LVEF improvement
Evaluation of efficacy of immunosuppressive therapy - PVC burden reduce
+1 more

Trial Design

1Treatment groups
Experimental Treatment
Group I: Patients with PVCsExperimental Treatment1 Intervention
Patients referred for management of symptomatic or asymptomatic PVCs. Patients presenting with PVCs and ventricular arrhythmias will be monitored using ILRs from the time of their initial presentation of PVCs.

Find a Location

Who is running the clinical trial?

Kansas City Heart Rhythm Research FoundationLead Sponsor
26 Previous Clinical Trials
11,922 Total Patients Enrolled
2 Trials studying Myocarditis
482 Patients Enrolled for Myocarditis
Dhanunjaya Lakkireddy, MDPrincipal InvestigatorKansas City Heart Rhythm Institute
28 Previous Clinical Trials
8,174 Total Patients Enrolled
2 Trials studying Myocarditis
482 Patients Enrolled for Myocarditis

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
Circulation: Arrhythmia and ElectrophysiologyJournal
Myocarditis Causing Premature Ventricular Contractions
Lakkireddy, Dhanunjaya, Mohit K. Turagam, Bharath Yarlagadda, Tawseef Dar, Mark Hamblin, Megan Krause, Valay Parikh, et al.. 2019. “Myocarditis Causing Premature Ventricular Contractions”. Circulation: Arrhythmia and Electrophysiology. Ovid Technologies (Wolters Kluwer Health). doi:10.1161/circep.119.007520.
Clinical Case ReportsJournal
Electrical Storm in the Inflamed Heart: Ventricular Tachycardia Due to Myocarditis
Mattsson, Gustav, and Peter Magnusson. 2017. “Electrical Storm in the Inflamed Heart: Ventricular Tachycardia Due to Myocarditis”. Clinical Case Reports. Wiley. doi:10.1002/ccr3.1071.
MedicineJournal
Increased Risk of Ventricular Tachycardia and Cardiovascular Death in Patients with Myocarditis During the Long-term Follow-up
Te, Abigail Louise D., Tao-Cheng Wu, Yenn-Jiang Lin, Yun-Yu Chen, Fa-Po Chung, Shih-Lin Chang, Li-Wei Lo, et al.. 2017. “Increased Risk of Ventricular Tachycardia and Cardiovascular Death in Patients with Myocarditis During the Long-term Follow-up”. Medicine. Ovid Technologies (Wolters Kluwer Health). doi:10.1097/md.0000000000006633.
HerzJournal
Immunosuppressive Therapy in Virus-negative Inflammatory Cardiomyopathy
Frustaci, A., and C. Chimenti. 2012. “Immunosuppressive Therapy in Virus-negative Inflammatory Cardiomyopathy”. Herz. Springer Science and Business Media LLC. doi:10.1007/s00059-012-3694-x.
~11 spots leftby Dec 2024
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