This trial is evaluating whether Similac Human Milk Fortifier Hydrolyzed Protein Concentrated Liquid will improve 3 primary outcomes and 5 secondary outcomes in patients with Breast Milk. Measurement will happen over the course of 30 days.
This trial requires 78 total participants across 2 different treatment groups
This trial involves 2 different treatments. Similac Human Milk Fortifier Hydrolyzed Protein Concentrated Liquid is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.
"A well-balanced diet is good for the infant's health and improves the likelihood of survival. Breast feeding for an infant that is premature is strongly associated with favourable survival rates." - Anonymous Online Contributor
"Premature birth is a significant determinant of an array of health complications during childhood and is associated with increased risk of later cardiovascular disease. Premature birth is the second most frequent cause of childhood death in industrialized countries in spite of the growing experience with neonatal care and the availability of effective intervention. Future research needs to address the challenges in defining premature birth in terms of definition, prevention, and timely intervention." - Anonymous Online Contributor
"Some signs of premature birth are easy to identify (delayed caput, apgar score<3, fetal heart rate >120 beats per minute). More subtle features may be overlooked. In any given patient, signs are unlikely to be sufficiently specific for a diagnosis of premature birth." - Anonymous Online Contributor
"Infants with severe congenital anomalies should be followed with ultrasound examinations and clinical checkups to monitor the growth of the fetus and the progress of the physical development of the fetus. During the ultrasound, the fetal health and the progress of the fetus should be monitored in terms of the condition of the fetal head and fetal face. After the fetus is discharged, the newborn should be followed regularly to detect any abnormal physical development and to monitor if the growth of the fetus is at a desirable pace. Once the fetus is discharged, the patient can be followed up at a pediatric department for 3-15 years." - Anonymous Online Contributor
"Most premature births occur in the 37th week of pregnancy and about 20% occur at or after 36 weeks. There are around 3.5 million premature births per year in the United States." - Anonymous Online Contributor
"Preterm birth is related to many risk factors. The leading risk factor for PTB is infertility, which may be related through some as yet unclear pathways to oxidative stress at a fetal-maternal interface." - Anonymous Online Contributor
"Although this study was limited in its sample size and retrospective nature, our results suggest that there is an association between premature birth, as defined in this study, and adverse sequelae (and early and late mortality) in later-surviving children." - Anonymous Online Contributor
"fortistrobin-treated milk formulas with a high protein:fat concentration of 2.36% can be safely used as a supplement to treat breast-fed infants with a significant decrease in allergen-induced symptoms." - Anonymous Online Contributor
"Human milk concentrates are formulated with different hydrolyzed proteins. They may all have advantages over standard human milk. The current study suggests that human milk concentrates containing hydrolyzed proteins may be beneficial in premature infants. Further research is warranted." - Anonymous Online Contributor
"A single dose of Similac (HPLC) is no different in breast-feeding than placebo with regard to incidence of respiratory infections. Data from a recent study from the current study suggest that HPLC-concentrated LPN does not significantly reduce the risk of bronchiolitis during the first 6 months of life." - Anonymous Online Contributor
"These data suggest that clinicians should not hesitate in offering clinical trials even to patients who would consider taking them due to concerns about premature birth." - Anonymous Online Contributor
"There is still much work to be done. The strongest evidence is for a reduction in the rate of preterm birth following treatment with progesterone or progestogen alone. The evidence for the effectiveness of preterm birth prevention with progesterone or progestogen on low birthweight and small for gestational age children is unclear." - Anonymous Online Contributor