← Back to Search

Other

Heat Therapy for Prediabetes (HOTFUN Trial)

N/A
Waitlist Available
Led By Paige Geiger, PhD
Research Sponsored by University of Kansas Medical Center
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up at baseline and post-intervention (~4-5 weeks after first visit)
Awards & highlights

HOTFUN Trial Summary

This study is evaluating whether heat treatment can improve sensory function in people with diabetes.

Eligible Conditions
  • Neuropathy
  • Prediabetes

HOTFUN Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~at baseline and post-intervention (~4-5 weeks after first visit)
This trial's timeline: 3 weeks for screening, Varies for treatment, and at baseline and post-intervention (~4-5 weeks after first visit) for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in 2-hr Glucose
Change in Fasting Blood Glucose (FBG)
Change in intraepidermal nerve fibers (IENF)
Secondary outcome measures
Change in Quantitative Sensory Testing (QST) scores
Change in concentration of Heat Shock Protein 25
Change in concentration of Heat Shock Protein 72
+2 more

HOTFUN Trial Design

1Treatment groups
Experimental Treatment
Group I: Heat Therapy TreatmentExperimental Treatment1 Intervention
This study will recruit subjects to participate in heat therapy treatment at the University of Kansas Medical Center (KUMC). After pre-screening, informed consent, and enrollment, all subjects will have baseline laboratory assessments as well as an examination for neuropathy and a lower distal leg biopsy (3mm). Subjects will complete 12 heat therapy treatments over the course of 4 weeks. Within 24-48 hours after the last heat therapy experience, post-treatment laboratory assessments as well as an examination for neuropathy and a lower distal leg biopsy (3mm) will be performed.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Heat Therapy
2019
N/A
~90

Find a Location

Who is running the clinical trial?

University of Kansas Medical CenterLead Sponsor
463 Previous Clinical Trials
169,267 Total Patients Enrolled
Paige Geiger, PhDPrincipal InvestigatorUniversity of Kansas Medical Center
1 Previous Clinical Trials
8 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Heat Shock Therapy to Improve Mitochondrial Function in Neuropathy
Paige Geiger, PhD 2020. "Heat Shock Therapy to Improve Mitochondrial Function in Neuropathy". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05070741.
~1 spots leftby Apr 2025
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top