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Blood Pressure Management for Postpartum Pre-eclampsia (MOPP Trial)

N/A
Waitlist Available
Led By Deepika Sagaram, MD
Research Sponsored by Rutgers, The State University of New Jersey
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up one year from delivery
Awards & highlights

MOPP Trial Summary

This trial looks at whether lower BP meds and better BP control reduces ER visits in post-pregnant women with high BP.

Who is the study for?
This trial is for postpartum individuals who have had chronic hypertension, gestational hypertension, or preeclampsia and delivered a baby after 20 weeks. Participants must be at least 18 years old, speak English or Spanish, able to follow instructions and consent to the study. They should plan on following up with certain associated hospitals but can't join if they're unwilling to monitor blood pressure at home or have conditions conflicting with the study protocol.Check my eligibility
What is being tested?
The trial is testing whether tighter control of blood pressure after childbirth using medication and remote monitoring can reduce emergency room visits in patients with hypertensive diseases like preeclampsia.See study design
What are the potential side effects?
Potential side effects may include reactions to antihypertensive medications such as dizziness, headache, fatigue, nausea, or other symptoms related to changes in blood pressure management.

MOPP Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~one year from delivery
This trial's timeline: 3 weeks for screening, Varies for treatment, and one year from delivery for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Postpartum Emergency Department visits for hypertensive disorders
Secondary outcome measures
Blood pressure at the postpartum visit
Breastfeeding rates at 6 weeks postpartum
Compliance with follow up at postpartum visits
+6 more

MOPP Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Prospective interventional armExperimental Treatment1 Intervention
The prospective cohort will identify patients in the postpartum period of their delivery hospitalization who are at risk of readmission for hypertensive disorders in the initial six weeks postpartum. Those at risk include patients with diagnosed with chronic hypertension or PIH. Chronic hypertension is defined as either taking antihypertensive medications or a blood pressure of greater than or equal to 140/90 mm Hg prior to 20 weeks of gestation. Pregnancy induced hypertension includes gestational hypertension, preeclampsia without severe features, preeclampsia with severe features and Hemolysis, Elevated Liver enzymes and Low Platelets (HELLP). The minimum requirement to be diagnosed with this spectrum of disorders is having two blood pressures of greater than or equal to 140/90 mm Hg during the antepartum, intrapartum or postpartum periods.
Group II: Retrospective observational armActive Control1 Intervention
The retrospective cohort will include all patients diagnosed with chronic hypertension or pregnancy-induced hypertensive (PIH) disorders at Robert Wood Johnson University Hospital and Cooperman Barnabas Medical Center in the past two years, including those presenting to the Emergency Department or readmitted for hypertensive disorders, during the immediate six weeks postpartum.

Find a Location

Who is running the clinical trial?

Rutgers, The State University of New JerseyLead Sponsor
429 Previous Clinical Trials
63,840 Total Patients Enrolled
Deepika Sagaram, MDPrincipal InvestigatorRutgers, Robert Wood Johnson

Media Library

Tight postpartum blood pressure control (Other) Clinical Trial Eligibility Overview. Trial Name: NCT05775744 — N/A
Pre-eclampsia Research Study Groups: Prospective interventional arm, Retrospective observational arm
Pre-eclampsia Clinical Trial 2023: Tight postpartum blood pressure control Highlights & Side Effects. Trial Name: NCT05775744 — N/A
Tight postpartum blood pressure control (Other) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05775744 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Can individuals currently enroll in this research trial?

"According to clinicaltrials.gov, this particular medical trial began recruiting patients on March 13th 2023 and has since ceased recruitment activity; as of now, 89 other investigations are actively seeking volunteers."

Answered by AI
Recent research and studies
clinicaltrials.govStudy
Management of Postpartum Preeclampsia
Deepika Sagaram, MD 2023. "Management of Postpartum Preeclampsia". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05775744.
~196 spots leftby Apr 2025
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