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Oxytocic Agent

Carbetocin 10mcg for Postpartum Hemorrhage

N/A

Waitlist Available

Led By Jose Carvalho, MD

Research Sponsored by Samuel Lunenfeld Research Institute, Mount Sinai Hospital

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be between 18 and 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 24 hours

Awards & highlights

Study Summary

This trial is being done to see if a smaller dose of a drug called carbetocin is effective in achieving adequate uterine tone at elective cesarean section in women with multiple pregnancies.

Eligible Conditions

Postpartum Hemorrhage
Twins

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 24 hours

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~24 hours

This trial's timeline: 3 weeks for screening, Varies for treatment, and 24 hours for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Uterine tone 2 minutes: questionnaire

Secondary outcome measures

Additional uterotonics administered

Bradycardia: heart rate less than 70% of baseline

Estimated blood loss

+13 more

Trial Design

6Treatment groups

Active Control

Group I: Carbetocin 10mcgActive Control1 Intervention

Patient is given 10mcg of carbetocin intravenously over 1 minute, immediately upon delivery of the fetal head.

Group II: Carbetocin 20mcgActive Control1 Intervention

Patient is given 20mcg of carbetocin intravenously over 1 minute, immediately upon delivery of the fetal head.

Group III: Carbetocin 100mcgActive Control1 Intervention

Patient is given 100mcg of carbetocin intravenously over 1 minute, immediately upon delivery of the fetal head.

Group IV: Carbetocin 60mcgActive Control1 Intervention

Patient is given 60mcg of carbetocin intravenously over 1 minute, immediately upon delivery of the fetal head.

Group V: Carbetocin 40mcgActive Control1 Intervention

Patient is given 40mcg of carbetocin intravenously over 1 minute, immediately upon delivery of the fetal head.

Group VI: Carbetocin 80mcgActive Control1 Intervention

Patient is given 80mcg of carbetocin intravenously over 1 minute, immediately upon delivery of the fetal head.

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Who is running the clinical trial?

Samuel Lunenfeld Research Institute, Mount Sinai HospitalLead Sponsor

127 Previous Clinical Trials

11,207 Total Patients Enrolled

30 Trials studying Postpartum Hemorrhage

1,695 Patients Enrolled for Postpartum Hemorrhage

Jose Carvalho, MDPrincipal InvestigatorMOUNT SINAI HOSPITAL

13 Previous Clinical Trials

664 Total Patients Enrolled

4 Trials studying Postpartum Hemorrhage

200 Patients Enrolled for Postpartum Hemorrhage

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does this study accept participants aged 65 and above?

"The age range of eligible participants, as outlined in the study's inclusion criteria, is 18 to 55 years old."

Answered by AI

What is the upper limit for participation in this experiment?

"Affirmative. Clinicaltrials.gov hosts data showing that this scientific trial, which was first posted on October 14th 2021, is actively seeking for patient enrolment. 30 participants must be recruited from 1 location."

Answered by AI

In what circumstances is Carbetocin 60mcg typically administered?

"Carbetocin 60mcg is commonly prescribed to treat postpartum hemorrhage but has also been found effective in preventing uterine atony, managing PPH (postpartum haemorrhage), and countering occurrences of uterine atony."

Answered by AI

Are there openings to enroll in this research trial at present?

"Per the information available on clinicaltrials.gov, it is clear that this medical research project is actively recruiting participants. This trial was initially posted on October 14th 2021 and most recently updated November 17th 2022."

Answered by AI

Would I be qualified to participate in this research?

"To be considered for this clinical trial, applicants must have experienced postpartum hemorrhage and fall between the ages of 18 - 55. As such, a total of 30 participants are being recruited."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Carbetocin at Elective Cesarean Deliveries: A Dose-finding Study in Women With Twin Pregnancy.

2021. "Carbetocin at Elective Cesarean Deliveries: A Dose-finding Study in Women With Twin Pregnancy.". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04182360.