Brain Stimulation for Negative Emotions
What You Need to Know Before You Apply
What is the purpose of this trial?
The goal of this clinical trial is to learn whether non-invasive brain stimulation, called transcranial temporal interference stimulation (tTIS), can reduce negative affect, and how expectations shaped by care providers influence these effects.The main questions this study aims to answer are: (1)Does active tTIS reduce negative affect more effectively than sham (inactive) tTIS? (2)Do positive treatment expectations enhance the effects compared to negative expectations?Participants will: (1) Receive either active or sham tTIS. (2) Be provided with positive or negative messaging regarding treatment effectiveness. (3) Interact with care providers and complete assessments measuring negative affect and physiological responses.
Are You a Good Fit for This Trial?
This trial is for individuals interested in exploring how brain stimulation and care provider expectations affect emotions. Participants will undergo non-invasive brain stimulation and receive messages about treatment effectiveness to measure changes in their emotional state.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Experiment 1
Participants complete four sessions with different combinations of active and sham tTIS and placebo messaging.
Experiment 2
Participants complete two sessions focusing on placebo manipulation effects with sham tTIS.
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Transcranial Temporal Interference Stimulation (tTIS)
Find a Clinic Near You
Who Is Running the Clinical Trial?
Trustees of Dartmouth College
Lead Sponsor