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DBT + Escitalopram for Borderline Personality Disorder

N/A
Waitlist Available
Led By Marianne Goodman, MD
Research Sponsored by Bronx VA Medical Center
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 5 years
Awards & highlights

Study Summary

This trial is testing whether the addition of the antidepressant escitalopram to Dialectical Behavior Therapy (DBT) is more effective than DBT alone in treating adolescents with major depression.

Who is the study for?
This trial is for men and women aged 18-60 with Borderline Personality Disorder, who haven't taken any psychotropic medications for at least 2 weeks. It's not open to those with Schizophrenia, Bipolar Disorder, Mental Retardation, Substance Dependence or current Major Depression. Participants also shouldn't be in other individual psychotherapy.Check my eligibility
What is being tested?
The study tests Dialectical Behavior Therapy (DBT) combined with either the antidepressant escitalopram or a placebo over six months. DBT includes weekly group and individual sessions plus therapist availability by phone. Participants are randomly assigned to receive either the medication or placebo.See study design
What are the potential side effects?
While side effects specific to DBT aren't mentioned, escitalopram can cause nausea, sleep issues, fatigue, dry mouth and increased sweating among others. Placebo effects vary but can include symptoms participants believe are related to treatment.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 5 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 5 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Measures of impulsivity, aggression, affective impulsivity, immediate and delayed memory, and cognitive processing at baseline, 6 months and 9 months

Find a Location

Who is running the clinical trial?

Bronx VA Medical CenterLead Sponsor
20 Previous Clinical Trials
1,286 Total Patients Enrolled
1 Trials studying Borderline Personality Disorder
Marianne Goodman, MDPrincipal InvestigatorBronx VA Medical Center/Mount Sinai School of Medicine
3 Previous Clinical Trials
113 Total Patients Enrolled
2 Trials studying Borderline Personality Disorder
22 Patients Enrolled for Borderline Personality Disorder

Media Library

Dialectical Behavior Therapy (DBT) Clinical Trial Eligibility Overview. Trial Name: NCT00255554 — N/A
Borderline Personality Disorder Research Study Groups:
Borderline Personality Disorder Clinical Trial 2023: Dialectical Behavior Therapy (DBT) Highlights & Side Effects. Trial Name: NCT00255554 — N/A
Dialectical Behavior Therapy (DBT) 2023 Treatment Timeline for Medical Study. Trial Name: NCT00255554 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is the age threshold for this clinical trial higher than eighty-five years?

"The selection criteria for this medical investigation necessitates that participants be between 18 and 60 years old. Conversely, there are 251 trials available to people under the age of majority and 636 studies open to senior citizens."

Answered by AI

Who else is applying?

What state do they live in?
New Jersey
New York
How old are they?
18 - 65
What site did they apply to?
Bronx VA Medical Center
What portion of applicants met pre-screening criteria?
Met criteria
Recent research and studies
clinicaltrials.govStudy
DBT and Escitalopram in Borderline Personality Disorder
2024. "DBT and Escitalopram in Borderline Personality Disorder". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT00255554.
All > Obsessive Compulsive Disorder > Borderline Personality Disorder
~233 spots leftby Apr 2025
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