Personalized Condition for Emotional Regulation

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Emotional Regulation+6 MoreChecking the Facts - Behavioral
Eligibility
18+
All Sexes
What conditions do you have?
Select

Study Summary

The proposed study is designed to first test whether teaching people personalized or standardized emotion regulation skills leads to greater decreases in daily negative emotion intensity. Second, using data from an initial sample, the investigators will prospectively assign an independent sample of participants to receive their predicted optimal or non-optimal skills to determine if it is feasible and efficacious to match participants to the most appropriate training condition. Results of these studies may identify the mechanisms by which emotion regulation interventions impact emotional functioning and allow for the development of personalized, evidence-based, and scalable emotion regulation interventions.

Eligible Conditions
  • Emotional Regulation
  • Obsessive-Compulsive Disorder
  • Eating Disorders
  • Post Traumatic Stress Disorder
  • Borderline Personality Disorder
  • Depression
  • Anxiety

Treatment Effectiveness

Study Objectives

1 Primary · 7 Secondary · Reporting Duration: Once every 2 weeks for 6 weeks (4 times total)

Day 42
Changes in Positive and Negative Affect Schedule-Short Form
Day 48
Changes in emotion regulation effectiveness
Week 6
Changes in Breath-Counting Task
Changes in Five-Factor Model Score Sheet
Changes in Hamilton Anxiety Rating Scale
Changes in Hamilton Depression Rating Scale
Changes in Opposite to Emotion Action Task
Changes in Ways of Responding Scale

Trial Safety

Trial Design

2 Treatment Groups

Personalized Condition
1 of 2
Standardized Condition
1 of 2

Active Control

390 Total Participants · 2 Treatment Groups

Primary Treatment: Personalized Condition · No Placebo Group · N/A

Personalized ConditionActiveComparator Group · 3 Interventions: Checking the Facts, Mindfulness of Current Emotions, Opposite to Emotion Action · Intervention Types: Behavioral, Behavioral, Behavioral
Standardized ConditionActiveComparator Group · 3 Interventions: Checking the Facts, Mindfulness of Current Emotions, Opposite to Emotion Action · Intervention Types: Behavioral, Behavioral, Behavioral

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: once every 2 weeks for 6 weeks (4 times total)

Who is running the clinical trial?

Matthew SouthwardLead Sponsor
National Institute of Mental Health (NIMH)NIH
2,555 Previous Clinical Trials
1,823,369 Total Patients Enrolled
1 Trials studying Emotional Regulation
838 Patients Enrolled for Emotional Regulation
Matthew W Southward, Ph.D.Principal InvestigatorUniversity of Kentucky

Eligibility Criteria

Age 18+ · All Participants · 1 Total Inclusion Criteria

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Who else is applying?

What portion of applicants met pre-screening criteria?
Did not meet criteria100.0%
Why did patients apply to this trial?
  • "i've tried many ways but failed"
How many prior treatments have patients received?
1100.0%