Neuromodulation for Peripheral Neuropathy
What You Need to Know Before You Apply
What is the purpose of this trial?
To learn if a process called neuromodulation can help to improve pain due to CIP
Do I need to stop my current medications for the trial?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
Is spinal cord stimulation (SCS) safe for humans?
Spinal cord stimulation (SCS) has been used for various conditions like chronic pain and angina, and studies show it is generally safe for humans. It is a well-established therapy with long-term safety data available, indicating it is not more invasive than other common procedures like cardiac pacing.12345
How is the neuromodulation treatment for peripheral neuropathy different from other treatments?
This treatment uses neuromodulation, specifically spinal cord stimulation (SCS), which is unique because it targets the nervous system directly to manage pain, unlike standard medications that often provide only modest relief. It includes both conventional low-frequency and high-frequency SCS, offering options that are either paresthesia-dependent or independent, making it a novel approach for those with chronic neuropathic pain.678910
What data supports the effectiveness of this treatment for peripheral neuropathy?
Spinal cord stimulation (SCS) has been shown to improve blood flow and relieve pain in diabetic patients with peripheral arterial disease, and it has been used successfully for other conditions like ischemic heart disease and peripheral vascular disease, suggesting potential benefits for peripheral neuropathy.911121314
Who Is on the Research Team?
Saba Javed, M D
Principal Investigator
M.D. Anderson Cancer Center
Are You a Good Fit for This Trial?
This trial is for adults aged 18-85 with chemo-induced peripheral neuropathy (CIPN) from specific drugs like vinca alkaloids, taxanes, and platinum-based compounds. Participants must understand the study and consent to join. It's not for those with cognitive issues, recent substance abuse, other types of neuropathy, skin lesions or current infections.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive neuromodulation treatment to assess its effect on chemo-induced peripheral neuropathy
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Abbott® DRG / Abbott®/Medtronic® SCS
- Control Group
Abbott® DRG / Abbott®/Medtronic® SCS is already approved in United States, European Union for the following indications:
Find a Clinic Near You
Who Is Running the Clinical Trial?
M.D. Anderson Cancer Center
Lead Sponsor
Foundation for Anesthesia Education and Research
Collaborator