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Best Practice Advisory for Peripheral Artery Disease

N/A

Waitlist Available

Led By Aaron W Aday, MD, MSc

Research Sponsored by Vanderbilt University Medical Center

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up baseline, upon patient discharge through study completion, average of six months

Awards & highlights

Study Summary

This trial will focus on understanding how well a Best Practice Advisory for high-intensity statin therapy works in patients with Peripheral Artery Disease.

Who is the study for?

This trial is for adult patients hospitalized with Peripheral Artery Disease (PAD) at Vanderbilt University Medical Center who are not currently on high-intensity statins. Excluded are those with a history of statin allergy, rhabdomyolysis, hepatitis A/B/C, certain liver enzyme elevations, comfort measures only status, pregnancy or recent acute myocardial infarction or stroke.Check my eligibility

What is being tested?

The study is examining the effect of a Best Practice Advisory alert system on how often doctors prescribe high-intensity statins to PAD patients. It aims to see if this reminder increases the prescription rates for appropriate treatment.See study design

What are the potential side effects?

While side effects aren't directly studied in this trial as it focuses on prescription practices rather than drug effects, common side effects of high-intensity statins include muscle pain, increased risk of diabetes and liver damage.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ baseline, upon patient discharge through study completion, average of six months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~baseline, upon patient discharge through study completion, average of six months

This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, upon patient discharge through study completion, average of six months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Frequency of High-Intensity Statin Prescription at 90 days post-discharge

Frequency of High-Intensity Statin Prescription at discharge

Secondary outcome measures

Frequency of a Composite of Cardiovascular Events

Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: InterventionExperimental Treatment1 Intervention

Patients randomized to the intervention arm will have a Best Practice Advisory (BPA) displayed as part of the discharge order workflow. This BPA requires clinicians to choose an option before completing the discharge documentation. Options include ordering one of the appropriate statins or documenting that the medication is contraindicated, the patient declined, or the patient does not meet criteria for a high-intensity statin.

Group II: Usual CareActive Control1 Intervention

Patients randomized to the usual care arm will have the identical set of windows displayed in the discharge workflow minus the BPA window.

Do I qualify?Apply below to find out

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Who is running the clinical trial?

Vanderbilt University Medical CenterLead Sponsor

856 Previous Clinical Trials

672,040 Total Patients Enrolled

3 Trials studying Peripheral Arterial Disease

655 Patients Enrolled for Peripheral Arterial Disease

Aaron W Aday, MD, MScPrincipal InvestigatorVUMC Cardiovascular Medicine

Media Library

Best Practice Advisory Clinical Trial Eligibility Overview. Trial Name: NCT05166187 — N/A

Peripheral Arterial Disease Research Study Groups: Intervention, Usual Care

Peripheral Arterial Disease Clinical Trial 2023: Best Practice Advisory Highlights & Side Effects. Trial Name: NCT05166187 — N/A

Best Practice Advisory 2023 Treatment Timeline for Medical Study. Trial Name: NCT05166187 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there any open slots remaining in this study?

"Affirmative. The clinicaltrials.gov repository confirms that this medical trial began recruiting on April 20th 2022, and has since been edited November 8th of the same year. A total of 150 participants are sought from a single site for enrollment."

Answered by AI

How many candidates has this trial been able to accept thus far?

"Correct. Based on the clinicaltrials.gov database, this ongoing medical trial was first posted on April 20th 2022 and is currently recruiting 150 individuals from a single research site."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Best Practice Advisory to Initiate High-Intensity Statin Therapy in Patients With Peripheral Artery Disease

Aaron W. Aday, MD, MSc 2022. "Best Practice Advisory to Initiate High-Intensity Statin Therapy in Patients With Peripheral Artery Disease". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05166187.