Hemodialysis Timing for Kidney Failure
(POD-ESKD Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
The goal of this clinical trial is to evaluate the feasibility of two different preoperative hemodialysis schedules for people with end-stage kidney disease (ESKD) who undergo surgical procedures. The main questions it aims to answer are:
Is it feasible to randomize participants with ESKD undergoing nonemergent surgical procedures to same-day hemodialysis versus no same-day hemodialysis?
Is it safe to randomize participants with ESKD undergoing nonemergent surgical procedures to same-day hemodialysis versus no same-day hemodialysis?
Researchers will compare the two hemodialysis schedules to see if the scheduling and safety profiles are the same.
Participants will:
Answer questions about their health up to 4 weeks before and 4 weeks after the surgical procedure.
Receive hemodialysis on the day of the surgical procedure or not, depending on the study treatment assignment.
Who Is on the Research Team?
Vikram Fielding-Singh, MD, JD
Principal Investigator
Stanford University
Are You a Good Fit for This Trial?
This trial is for people with end-stage kidney disease (ESKD) who have been on a stable hemodialysis schedule for at least 90 days before their non-emergency surgery. They must be willing to follow the study's procedures and can't participate if they don't meet these requirements.Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Preoperative Assessment
Participants answer questions about their health up to 4 weeks before the surgical procedure
Treatment
Participants receive hemodialysis on the day of the surgical procedure or not, depending on the study treatment assignment
Follow-up
Participants are monitored for safety and effectiveness after treatment, including assessment of 30-day postoperative outcomes
What Are the Treatments Tested in This Trial?
Interventions
- No Same-Day Hemodialysis
- Same-Day Hemodialysis
Trial Overview
The POD-ESKD Pilot Trial is testing whether it's feasible and safe to perform hemodialysis on the same day as surgery compared to not doing so. Participants will either receive hemodialysis on the day of their surgical procedure or they won't, based on random assignment.
How Is the Trial Designed?
2
Treatment groups
Experimental Treatment
Active Control
Participants will receive same-day hemodialysis, defined as a hemodialysis treatment prior to the surgical procedure but on the same calendar day as the surgical procedure (typically in the morning prior to the procedure).
Participants will not receive same-day hemodialysis, defined as a hemodialysis treatment prior to the surgical procedure but on the same calendar day as the surgical procedure.
Find a Clinic Near You
Who Is Running the Clinical Trial?
Stanford University
Lead Sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Collaborator
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