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Diseased periodontal treatment for Periodontitis

N/A
Waitlist Available
Led By Ikramuddin Aukhil
Research Sponsored by University of Florida
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 24 months
Awards & highlights

Study Summary

This trial will study the immunological and microbiological mechanisms of aggressive periodontitis in children, in order to better understand and treat the disease.

Eligible Conditions
  • Periodontitis

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~24 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and 24 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
SNPs and DNA methylation
Secondary outcome measures
Systemic inflammatory levels

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Diseased periodontal treatmentExperimental Treatment1 Intervention
Scaling and root planing along with systemic antibiotics (Amoxicillin 500 mg and Metronidazole 250 mg tid 7 days).
Group II: Conventional periodontal treatmentActive Control1 Intervention
Standard periodontal prophylaxis
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Diseased periodontal treatment
2006
N/A
~520

Find a Location

Who is running the clinical trial?

University of FloridaLead Sponsor
1,340 Previous Clinical Trials
715,164 Total Patients Enrolled
1 Trials studying Periodontitis
21 Patients Enrolled for Periodontitis
National Institute of Dental and Craniofacial Research (NIDCR)NIH
300 Previous Clinical Trials
847,830 Total Patients Enrolled
14 Trials studying Periodontitis
4,770 Patients Enrolled for Periodontitis
Ikramuddin AukhilPrincipal InvestigatorUniversity of Florida

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
Journal of PeriodontologyJournal
A New Look at the Etiology and Pathogenesis of Early-onset Periodontitis: Cementopathia Revisited
Page, Roy C., and David A. Baab. 1985. “A New Look at the Etiology and Pathogenesis of Early-onset Periodontitis: Cementopathia Revisited”. Journal of Periodontology. Wiley. doi:10.1902/jop.1985.56.12.748.
Journal of Periodontal ResearchJournal
Role of Cytokines in the Modulation of Neutrophil Chemotaxis in Localized Juvenile Periodontitis
Agarwal, S., J. B. Suzuki, and A. E. Riccelli. 1994. “Role of Cytokines in the Modulation of Neutrophil Chemotaxis in Localized Juvenile Periodontitis”. Journal of Periodontal Research. Wiley. doi:10.1111/j.1600-0765.1994.tb01101.x.
Journal of Clinical PeriodontologyJournal
Microbiological and Clinical Effects of Surgical Treatment of Localized Juvenile Periodontitis
Christersson, Lars A., Jorgen Slots, Bengt G. Rosling, and Robert J. Genco. 1985. “Microbiological and Clinical Effects of Surgical Treatment of Localized Juvenile Periodontitis”. Journal of Clinical Periodontology. Wiley. doi:10.1111/j.1600-051x.1985.tb01382.x.
Journal of Dental ResearchJournal
Hyper-responsive Phenotype in Localized Aggressive Periodontitis
Shaddox, L., J. Wiedey, E. Bimstein, I. Magnuson, M. Clare-Salzler, I. Aukhil, and S.M. Wallet. 2009. “Hyper-responsive Phenotype in Localized Aggressive Periodontitis”. Journal of Dental Research. SAGE Publications. doi:10.1177/0022034509353397.
~28 spots leftby Apr 2025
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