Live Music for Alzheimer's Disease
Trial Summary
Will I have to stop taking my current medications?
The trial does not specify if you need to stop taking your current medications, but you cannot participate if you have started a new prescription medication in the last 6 months or if you are prescribed Benzodiazepines on an as-needed basis.
What data supports the effectiveness of the treatment Live Music Session for Alzheimer's Disease?
Is live music therapy safe for people with Alzheimer's disease?
How does the Live Music Session treatment differ from other treatments for Alzheimer's disease?
What is the purpose of this trial?
This study aims to investigate the neurophysiological effects of live music on individuals with early Alzheimer's Disease (AD), dementia, and/or mild cognitive impairment (MCI) and their caregivers. Heart rate (HR), heart rate variability (HRV), and brain activity will be measured as participant-caregiver dyads listen to preferred and improvised music performed by professional musicians. Investigators will leverage various measurement techniques including, but not limited to, electroencephalography (EEG), behavioral, surveys, and physiological monitoring to study the impact of live music on anxiety in AD and inter-dyad synchrony.
Research Team
AZA Allsop, MD, PhD
Principal Investigator
Yale University
Eligibility Criteria
This trial is for early Alzheimer's patients and their caregivers. Participants should have a diagnosis of mild cognitive impairment, Alzheimer's Disease, or dementia. Caregivers can be foster parents or primary caregivers.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants attend live music performances and pre-recorded control session performances. Physiological and survey data are collected to assess the impact of music on anxiety, social motivation, parasympathetic activity, and neural synchrony.
Follow-up
Participants are monitored for changes in neurophysiological measures and emotional well-being after the music sessions.
Treatment Details
Interventions
- Live Music Session
Find a Clinic Near You
Who Is Running the Clinical Trial?
Yale University
Lead Sponsor
Yale University School of Medicine, Department of Psychiatry
Collaborator
NeuroArts Blueprint Initiative
Collaborator
Renée Fleming Foundation
Collaborator
Howard University
Collaborator