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Procedure

Flexible stimulation for Parkinson's Disease

N/A
Waitlist Available
Research Sponsored by University of Toronto
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up after 3 months of each intervention
Awards & highlights

Study Summary

Exploring the benefits of the linear lead in deep brain stimulation.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~after 3 months of each intervention
This trial's timeline: 3 weeks for screening, Varies for treatment, and after 3 months of each intervention for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change of Overall Global functioning (PGIC)
Secondary outcome measures
Cadence measured using Prokinetics gait analysis/Zeno Walkway
Change in the presence and severity of depressive symptoms using the Beck Depression Inventory (BDI)
Clinical change in motor symptoms
+6 more

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Flexible stimulationExperimental Treatment1 Intervention
Flexible stimulation using all available stimulation strategies provided by the VerciseTM system including stimulation of contacts 1-8 and variable pulse width and frequency.
Group II: Standard StimulationActive Control1 Intervention
Standard stimulation using contact 3-6 to achieve best therapeutic stimulation
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Deep brain stimulation
2010
Completed Phase 3
~380

Find a Location

Who is running the clinical trial?

University of TorontoLead Sponsor
689 Previous Clinical Trials
1,018,633 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
Age and AgeingJournal
The Parkinson's Disease Questionnaire (PDQ-39): Development and Validation of a Parkinson's Disease Summary Index Score
JENKINSON, CRISPIN, RAY FITZPATRICK, VIV PETO, RICHARD GREENHALL, and NIGEL HYMAN. 1997. “The Parkinson's Disease Questionnaire (PDQ-39): Development and Validation of a Parkinson's Disease Summary Index Score”. Age and Ageing. Oxford University Press (OUP). doi:10.1093/ageing/26.5.353.
clinicaltrials.govStudy
Flexible vs. Standard Deep Brain Stimulation Programming in Parkinson Disease Patients
Alfonso Fasano 2016. "Flexible vs. Standard Deep Brain Stimulation Programming in Parkinson Disease Patients". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04116177.
All > Parkinson
~1 spots leftby Apr 2025
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