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Deep Brain Stimulation

Directional Stimulation for Parkinson's Disease

N/A
Waitlist Available
Led By Alfonso Fasano, MD
Research Sponsored by University of Toronto
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Patients with a diagnosis of Parkinson's disease (PD) according to the British Parkinson's Disease Society Brain Bank criteria, who fulfilled the inclusion
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up throughout the study, averaging 6 months
Awards & highlights

Study Summary

Exploring directional lead

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~after 3 months of each intervention
This trial's timeline: 3 weeks for screening, Varies for treatment, and after 3 months of each intervention for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Number/incidence of adverse events
Secondary outcome measures
Cadence measured with the Zeno Walkway
Change from baseline in a measure of health related quality of life and non-motor symptoms of Parkinson's disease using the Parkinson's disease Questionnaire (PDQ-39)
Change in articulation rate of speech using a Phonetics Software
+12 more

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Directional StimulationExperimental Treatment1 Intervention
Participants will receive stimulation using the best segmented (steered) contacts.
Group II: Standard StimulationActive Control1 Intervention
Participants will receive stimulation using the best contact combination in ring mode.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Deep brain stimulation
2010
Completed Phase 3
~380

Find a Location

Who is running the clinical trial?

University of TorontoLead Sponsor
689 Previous Clinical Trials
1,018,623 Total Patients Enrolled
Alfonso Fasano, MDPrincipal InvestigatorUniversity of Toronto

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Expanding the Therapeutic Window of Deep Brain Stimulation in Parkinson's Disease by Means of Directional Leads
Alfonso Fasano 2018. "Expanding the Therapeutic Window of Deep Brain Stimulation in Parkinson's Disease by Means of Directional Leads". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04093544.
All > Parkinson
~3 spots leftby Apr 2025
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