SwallowFIT for Parkinson's Disease

GC
Overseen ByGiselle Carnaby, PhD, MPH
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: The University of Texas Health Science Center at San Antonio
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

The goal of this clinical trial is to learn if a proactive swallow exercise will help to improve swallow fitness in patients with Parkinson's disease.

The aim of the study is to assess how effective this exercise is and to measure the change in swallowing fitness from the beginning to the end of the study.

Patients who are given the exercise training will be compared to participants who are treated using the usual standard treatment.

Patients will have 6 weeks of twice-weekly SwallowFIT training. Each session will be an hour long.

Who Is on the Research Team?

GC

Giselle Carnaby, PhD, MP

Principal Investigator

The University of Texas Health Science Center at San Antonio

Are You a Good Fit for This Trial?

This trial is for individuals with Parkinson's Disease who are interested in improving their swallowing ability. Participants will engage in a proactive swallow exercise program over 6 weeks, with sessions twice a week.

Inclusion Criteria

I have been diagnosed with Parkinson's Disease, mainly showing tremors or stiffness.
Swallowing concern confirmed by Modified Unified Parkinson Disease Rating Scale (MDS-UPDRS) - ADL swallowing item >0 or Mann Assessment of Swallowing scale (MASA) score ≤185
Able to consume oral nutrition (Functional Oral Intake Score ≤ 6)
See 4 more

Exclusion Criteria

History of other neurological disease potentially causing dysphagia
Dementia (MMSE<20; Montreal cognitive assessment (MoCA) ≤ 20)
I am experiencing severe depression.
See 11 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive 6 weeks of twice-weekly SwallowFIT training, each session lasting one hour

6 weeks
12 visits (in-person)

Follow-up

Participants are monitored for safety and effectiveness after treatment

6 months

What Are the Treatments Tested in This Trial?

Interventions

  • SwallowFit

Trial Overview

The SwallowFIT study tests if special swallow exercises can improve swallowing fitness in Parkinson’s patients compared to those receiving standard treatment. The effectiveness of the exercises will be measured from start to end of the study.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Active Control

Group I: SwallowFit InterventionExperimental Treatment1 Intervention
Group II: Clinical Monitoring Only (CMO)Active Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

The University of Texas Health Science Center at San Antonio

Lead Sponsor

Trials
486
Recruited
92,500+

United States Department of Defense

Collaborator

Trials
940
Recruited
339,000+