Peppermint Oil for Urinary Retention

Age: 18+
Sex: Female
Trial Phase: Academic
Sponsor: TriHealth Inc.

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial explores whether peppermint oil vapor can assist women who have difficulty urinating after childbirth. Participants will be divided into two groups: one will inhale peppermint oil vapor, and the other will use a placebo (mineral oil vapor). The study will assess how quickly and effectively each vapor aids urination and enhances overall comfort. Women who have recently given birth and are experiencing difficulty urinating independently may be suitable candidates for this trial. As an unphased trial, it provides participants the chance to contribute to research that could enhance postpartum care.

Will I have to stop taking my current medications?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

Is there any evidence suggesting that this trial's treatments are likely to be safe?

Research has shown that peppermint oil is generally safe for people. However, it can cause minor irritation to the eyes, skin, and breathing passages, leading to discomfort if touched or inhaled excessively.

In the small amounts used in this trial, peppermint oil does not cause serious problems. High doses of one component, pulegone, have been linked to bladder issues, but the study uses much lower amounts.

Overall, most people tolerate peppermint oil vapors well. Prospective participants should consider these minor potential risks, but the trial is likely safe.12345

Why are researchers excited about this trial's treatments?

Unlike the standard treatments for urinary retention, which often involve medications or catheterization, peppermint oil offers a natural alternative. Peppermint oil is unique because it is administered through vapor, which may provide a non-invasive way to relieve symptoms. Researchers are excited about its potential to relax the urinary tract muscles due to its menthol content, which could enhance urinary flow without the side effects associated with more conventional treatments.

What evidence suggests that this trial's treatments could be effective for urinary retention?

Research has shown that peppermint oil might help with urinary retention, a condition where the bladder cannot empty completely. In this trial, participants will inhale peppermint oil vapor, which may relax muscles and reduce swelling, potentially easing bladder release. Some studies suggest peppermint oil can increase the likelihood of urinating independently, but the results are not yet strong enough to alter medical practices. Although the evidence remains inconclusive, early findings are promising, and further research could offer clearer insights. Participants in another arm of this trial will inhale a placebo vapor (mineral oil) for comparison.36789

Are You a Good Fit for This Trial?

This trial is for English-speaking women over 18 who've recently given birth at Bethesda North Mom Baby Unit and are having trouble urinating on their own. They must be able to use the toilet normally, without a bedpan. Women with peppermint allergies, asthma, active herpes lesions, or seizure disorders cannot participate.

Inclusion Criteria

Recently gave birth
Admitted to Bethesda North Mom Baby Unit
English speaking
See 1 more

Exclusion Criteria

You are allergic to peppermint.
I cannot use the toilet and need a bed pan.
I have a seizure disorder.
See 2 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

1-2 weeks

Treatment

Participants are exposed to vapor of peppermint oil or placebo to resolve urinary retention

1 hour
1 visit (in-person)

Follow-up

Participants are monitored for resolution of urinary retention and patient satisfaction

1 hour

What Are the Treatments Tested in This Trial?

Interventions

  • Mineral Oil
  • Peppermint oil vapors
Trial Overview The study is testing if inhaling peppermint oil vapors helps postpartum women urinate more easily compared to inhaling mineral oil (placebo). Participants will be randomly assigned to one of these two treatments and monitored for how well they can pee without help and their satisfaction levels.
How Is the Trial Designed?
2Treatment groups
Experimental Treatment
Placebo Group
Group I: Peppermint OilExperimental Treatment1 Intervention
Group II: PlaceboPlacebo Group1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

TriHealth Inc.

Lead Sponsor

Trials
103
Recruited
54,100+

Citations

Evaluating the use of peppermint oil for postpartum women ...This descriptive study provides preliminary data that peppermint oil could potentially be an effective intervention for urinary retention, but ...
Postpartum Urinary Retention With Essential OilsPeppermint oil increased spontaneous voiding; however, findings were not statistically significant to support its use in clinical practice. Limitations include ...
Peppermint Oil Vapor to Relieve Postpartum Urinary ...outcomes include increasing job satisfaction, reducing the incidence of second victim trauma, and improving staff retention.
Prevention of Postpartum Urinary Retention with ...Peppermint oil is estimated to be one of the modalities in preventing health problems through antioxidant, anti-inflammatory, and antispasmodic ...
Peppermint Oil for Urinary Retention · Info for ParticipantsTrial Overview The study is testing if inhaling peppermint oil vapors helps postpartum women urinate more easily compared to inhaling mineral oil (placebo).
Safety Data SheetPeppermint Oil. Manufacturer/Supplier Trade name: Manufacturer ... Thermal decomposition can lead to release of irritating gases and vapors.
Organic Peppermint Essential OilHealth Hazards: May cause eye and skin irritation. May cause respiratory and digestive tract irritation. Flammability Hazards: Non-flammable.
SAFETY DATA SHEETAdvice for non-emergency personnel: Do not breathe vapors, aerosols. Avoid substance contact. Ensure adequate ventilation.
Peppermint oil MSDS - Material Safety Data SheetDo not use water jet. Special Remarks on Fire Hazards: When heated to decomposition it emits acrid smoke and irritating fumes. Special Remarks ...
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