Local Anesthetics for Postoperative Pain in Thyroid Surgery
Trial Summary
Do I need to stop my current medications for this trial?
The trial does not specify if you need to stop taking your current medications. However, if you have a history of using chronic pain medications in the past 6 months, you may not be eligible to participate.
What data supports the effectiveness of the drug Bupivacaine for postoperative pain management in thyroid surgery?
Is the use of local anesthetics like Bupivacaine generally safe for humans?
How does the drug Bupivacaine with epinephrine differ from other treatments for postoperative pain in thyroid surgery?
Bupivacaine with epinephrine is unique because it is used as a local anesthetic directly infiltrated into the wound, which can significantly reduce postoperative pain and the need for opioids compared to not using any local anesthetic. This method targets pain at the surgical site, providing effective pain relief with minimal systemic side effects.4891011
What is the purpose of this trial?
The purpose of this study is to compare the efficacy of Bupivicaine and Lidocaine for postoperative pain control in thyroid surgery.
Research Team
Han Zhang, MD FRCSC
Principal Investigator
St. Joseph's Hospital Hamilton
Eligibility Criteria
This trial is for individuals with certain types of thyroid disease who are planning to undergo thyroid surgery and can stay in the hospital for at least 12 hours post-surgery. It's not suitable for those with a history of diabetes, narcotic abuse, chronic pain medication use, neck radiation therapy, coagulation defects, allergies to Bupivacaine or Lidocaine, advanced thyroid cancer stages or extensive previous surgeries.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Patients receive local infiltration with either Bupivacaine or Lidocaine before neck incision during thyroid surgery
Postoperative Monitoring
Participants are monitored for postoperative pain and analgesia utilization
Follow-up
Participants are monitored for complications and return of sensation at the surgical site
Treatment Details
Interventions
- Bupivacaine 0.5% with 1:200 000 epinephrine
- Lidocaine 2% with 1:100 000 epinephrine
Bupivacaine 0.5% with 1:200 000 epinephrine is already approved in United States, Canada, European Union for the following indications:
- Local anesthesia
- Postoperative pain
- Cesarean section
- Local anesthesia
- Postoperative pain
- Local anesthesia
- Regional anesthesia
Find a Clinic Near You
Who Is Running the Clinical Trial?
St. Joseph's Healthcare Hamilton
Lead Sponsor