Deep Brain Stimulation for Parkinson's Disease

"As per clinicaltrials.gov, this trial is no longer engaging with potential participants; the initial post-date was June 15th 2021 and it last updated on October 4th 2022. However, there are still plenty of other medical studies that need volunteers at present – 483 to be exact!"

"This investigation is looking for 10 individuals with Parkinson's disease aged between 18 and 75. Necessary criteria includes: movement disorder issues that necessitate the surgical implantation of deep brain stimulators, patient requesting surgery to address their condition, no motion-related abnormalities hinting at an alternative diagnosis or contraindicating medical procedure, capacity to adhere to study follow-up visits for neurological recording, testing of adaptive stimulation, and clinical evaluation., age range 21 -75 years old , inadequate relief from conventional medication as judged by a neurologist specialising in motor disorders , absence of significant cognitive impairment (score of 21 or higher on Montreal Cognitive Assessment"

"Participants of this clinical trial must be over 18 years old, yet younger than 75."

"According to Burroughs Wellcome, the primary outcome that will be evaluated in this trial across a two year span is motor learning task mean accuracy with closed-loop compared to open-loop deep brain stimulation (DBS). Additionally, investigators plan on assessing other variables including stride length as measured by Rover and Xsens devices in metres, five times sit to stand test results which are scored based off speed of transition from sitting to standing position and back again, along with MDS-UPDRS III scores ranging from 0 - 72 points."