HCP-Guided Exercise for Pancreatic Cancer

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Pancreatic CancerHCP-Guided Exercise Training Program - Behavioral
Eligibility
18 - 90
All Sexes
What conditions do you have?
Select

Study Summary

Pilot study evaluating the feasibility of a 2-4 week health care provider guided exercise intervention prior to surgery for pancreatic cancer.

Eligible Conditions
  • Pancreatic Cancer

Treatment Effectiveness

Study Objectives

1 Primary · 12 Secondary · Reporting Duration: Baseline, Final Study Visit (Between Weeks 2-4)

Week 2
Change in Number of Circulating CD8-Positive T Cells Expressing IL-15Ra as Assessed by Flow Cytometry
Change in Number of Tumor-Infiltrating CD8-Positive T Cells
Change in Number of Tumor-Infiltrating CD8-Positive T Cells Expressing CD3
T-Lymphocyte
Change in Number of Tumor-Infiltrating CD8-Positive T Cells Expressing IL-15Ra
Up to Week 4
Average Daily MET Rates
Minutes Spent in Rapid Eye Movement (REM) Sleep
Number of Intervention Arm Participants in Compliance with HCP Exercise Intervention
Number of Participants who Experience Adverse Events (AEs)
Number of Participants who Experience an Event that Leads to Delay in Surgical Resection
Time Spent in Moderate-to-Vigorous Physical Activity (MVPA)
Time Spent in Sedentary Behavior
Total Physical Activity Energy Expenditure

Trial Safety

Trial Design

2 Treatment Groups

Control
1 of 2
HCP-Guided Exercise
1 of 2

Active Control

Experimental Treatment

30 Total Participants · 2 Treatment Groups

Primary Treatment: HCP-Guided Exercise · No Placebo Group · N/A

HCP-Guided Exercise
Behavioral
Experimental Group · 1 Intervention: HCP-Guided Exercise Training Program · Intervention Types: Behavioral
ControlNoIntervention Group · 1 Intervention: Control · Intervention Types:

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: baseline, final study visit (between weeks 2-4)

Who is running the clinical trial?

NYU Langone HealthLead Sponsor
1,264 Previous Clinical Trials
753,561 Total Patients Enrolled
Paul Oberstein, MDPrincipal InvestigatorNYU Langone Medical Center

Eligibility Criteria

Age 18 - 90 · All Participants · 7 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
You are planned to have at least 2 weeks after completing the last neoadjuvant therapy and surgery.
You are able to engage in physical activity as determined by a physiatrist.