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Anti-metabolites

Chemotherapy/radiation/surgery for Pancreatic Cancer

N/A
Waitlist Available
Led By Manisha Palta, MD
Research Sponsored by Duke University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up approximately 6 months
Awards & highlights

Study Summary

This trial will test if a new combination of cancer drugs and radiation therapy is effective and safe for treating pancreatic cancer.

Eligible Conditions
  • Resectable Pancreatic Cancer

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~approximately 6 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and approximately 6 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Feasibility as Measured by Number of Participants Who Complete the Neoadjuvant Gemcitabine/Nab-paclitaxel and HIGRT Regimen
Secondary outcome measures
Number of Participants Experiencing Grade >/=2 Acute Toxicity
Number of Participants Who Received an R0 Resection
Number of Participants Who Underwent Surgical Resection

Trial Design

1Treatment groups
Experimental Treatment
Group I: Chemotherapy/radiation/surgeryExperimental Treatment4 Interventions
This is a single arm prospective study. All eligible subjects will recieve 2 cycles of neoadjuvant Gemcitabine/nab-Paclitaxel, followed by hypofractionated radiation therapy followed by surgical resection. Subjects may receive adjuvant chemotherapy post surgical resection at the clinical discretion of the medical oncologist.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Radiation therapy
2013
Completed Phase 3
~2850
Gemcitabine/nab-Paclitaxel
2015
N/A
~40
Adjuvant chemotheapy
2015
N/A
~40

Find a Location

Who is running the clinical trial?

Duke UniversityLead Sponsor
2,358 Previous Clinical Trials
3,420,029 Total Patients Enrolled
Manisha Palta, MDPrincipal InvestigatorDuke Health
7 Previous Clinical Trials
13,444 Total Patients Enrolled

Media Library

Gemcitabine/nab-Paclitaxel (Anti-metabolites) Clinical Trial Eligibility Overview. Trial Name: NCT02318095 — N/A
Pancreatic Cancer Research Study Groups: Chemotherapy/radiation/surgery
Pancreatic Cancer Clinical Trial 2023: Gemcitabine/nab-Paclitaxel Highlights & Side Effects. Trial Name: NCT02318095 — N/A
Gemcitabine/nab-Paclitaxel (Anti-metabolites) 2023 Treatment Timeline for Medical Study. Trial Name: NCT02318095 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is this study actively looking for more participants?

"Unfortunately, this clinical trial is not accepting patients at the moment. Although, it's worth mentioning that the study was initially posted on February 17th, 2015 and was most recently edited on May 6th, 2022. For other trials, 597 are currently recruiting for pancreas and 1164 for this specific treatment."

Answered by AI

To what number of people will this clinical trial have access?

"This study is no longer recruiting new patients, as evident by the clinical trial's last update on May 6th, 2022. If you are looking for other similar studies, 597 studies involving the pancreas are actively recruiting and 1164 studies for this type of treatment are admitting patients."

Answered by AI

Are there any other investigatory papers that explore this form of care?

"There are 1164 ongoing clinical trials related to this treatment, with 329 of them being in the third phase. The majority of these studies are based in Shanghai, but there are 59212 locations running these trials in total."

Answered by AI

What are the conditions that this medication is usually effective against?

"This treatment is commonly used to manage neoplasm metastasis, but it can also help patients with other conditions such as locally advanced non-small cell lung cancer, metastatic bladder cancer, and urinary bladder."

Answered by AI
~4 spots leftby Apr 2025