Genetic Testing for Pancreatic Cancer
(ACCELERATE Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
The goal of this study is to learn if the genetic information and proteins from tumours can help treat pancreatic ductal adenocarcinoma (PDAC). The main questions it aims to answer are:* Is it feasible to obtain genetic test results within a timeframe that can help inform treatment decisions for individuals with PDAC?* Can the genetic test results provide information about how a tumour will respond to or resist treatment?Participants will:* Receive standard chemotherapy to treat their cancer.* Provide samples of their blood, tissue, and fluid for genetic testing.* Visit the clinic every 4 weeks for check-ups and tests.* Complete questionnaires every 12 weeks.
Do I need to stop my current medications for the trial?
The trial protocol does not specify whether you need to stop taking your current medications. However, you will receive standard chemotherapy as part of the study, so it's best to discuss your current medications with the study team.
Is genetic testing for pancreatic cancer safe for humans?
How does genetic testing for pancreatic cancer differ from other treatments?
Genetic testing for pancreatic cancer is unique because it involves analyzing genetic mutations in the tumor and blood, which can help predict outcomes and guide treatment decisions. This approach is different from traditional treatments as it focuses on identifying specific genetic changes that may offer new therapeutic targets and improve early detection.36789
What data supports the effectiveness of the treatment Tumour DNA and Proteins for pancreatic cancer?
Who Is on the Research Team?
Daniel J Renouf, MD
Principal Investigator
BC Cancer
Are You a Good Fit for This Trial?
This trial is for individuals with pancreatic ductal adenocarcinoma (PDAC) who are receiving standard chemotherapy. They must be willing to provide blood, tissue, and fluid samples for genetic testing and attend clinic visits every 4 weeks.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive standard chemotherapy and provide samples for genetic testing
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Tumour DNA and Proteins
Find a Clinic Near You
Who Is Running the Clinical Trial?
British Columbia Cancer Agency
Lead Sponsor
Terry Fox Research Institute
Collaborator
BC Cancer Foundation
Collaborator