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Local Anesthetic

The nerve block group for Postoperative Pain

N/A
Waitlist Available
Research Sponsored by Western University, Canada
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
patients undergoing cardiac surgical procedures performed by a single conventional median sternotomy, and first case of the day patient because early postoperative pain scores are difficult to obtain overnight for patients admitted to the ICU in the evening.
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up from the time of first recruitment up to one month
Awards & highlights

Study Summary

The TTP block is a novel regional anesthetic technique that shows promise in providing analgesia for anterior chest wall incisions and median sternotomy. The investigators hope to show that by providing the TTP block, there will be reduced early postoperative pain, reduced sedation and shallow breathing, reduced time on breathing machine, leading to an increase in patient comfort and satisfaction. The investigators also hope the decreased need for pain medication and reduced time on the breathing machine will translate into decreased nursing workload.

Eligible Conditions
  • Postoperative Pain
  • Caudal Epidural Block Therapy
  • Cardiac Surgery

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~from the time of first recruitment up to one month
This trial's timeline: 3 weeks for screening, Varies for treatment, and from the time of first recruitment up to one month for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Narcotic requirements equivalents
Secondary outcome measures
Oxygen saturation by pulse oximetry
Pain score equivalents
Patient satisfaction satisfaction
+2 more
Other outcome measures
Acceptability
Nausea/Vomiting
Recruitment rate

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: The nerve block groupExperimental Treatment5 Interventions
TTP block under dynamic ultrasound guidance plus the standard care (hydromorphone, fentanyl, aspirin, acetaminophen)
Group II: The standard of care groupActive Control4 Interventions
Patients in the standard care group will receive pain medications, such as hydromorphone, fentanyl, aspirin and acetaminophen.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Acetylsalicylic acid
FDA approved
Fentanyl
FDA approved
Acetaminophen
FDA approved
Hydromorphone
FDA approved

Find a Location

Who is running the clinical trial?

Western University, CanadaLead Sponsor
239 Previous Clinical Trials
57,383 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
Regional Anesthesia & Pain MedicineJournal
Transversus Thoracis Muscle Plane Block in Cardiac Surgery: A Pilot Feasibility Study
Fujii, Satoru, Matthew Roche, Philip M Jones, Deepti Vissa, Daniel Bainbridge, and Jian Ray Zhou. 2019. “Transversus Thoracis Muscle Plane Block in Cardiac Surgery: A Pilot Feasibility Study”. Regional Anesthesia & Pain Medicine. BMJ. doi:10.1136/rapm-2018-100178.
clinicaltrials.govStudy
Analgesic Effects of Transversus Thoracic Plane (TTP) Block in Cardiac Surgery
Satoru Fujii 2017. "Analgesic Effects of Transversus Thoracic Plane (TTP) Block in Cardiac Surgery". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03128346.
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