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Yoga vs Running for Metabolic Health (TrainMeUpMN Trial)

N/A
Waitlist Available
Led By Lisa S. Chow, MD
Research Sponsored by University of Minnesota
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
For overweight or obese subjects: Insulin resistant based on screening oral glucose tolerance testing, BMI 25 to 40 kg/m2 inclusive, stable weight for at least 3 months (± 5 lbs.), sedentary status (self-report < 30 minutes/week regular exercise)
All subjects must be 18 to 40 years of age and capable of giving informed consent
Timeline
Screening 3 weeks
Treatment Varies
Follow Up before and after exercise program (exercise program will take 16 weeks, expected average for evaluation will be 20 weeks)
Awards & highlights

TrainMeUpMN Trial Summary

This trial is testing how different types of exercise affect how the body processes fat and how this affects insulin resistance. It is looking specifically at the effects of weight and training on insulin resistance. The trial will study people before and after supervised aerobic or yoga training and test these differences using stable isotopes.

Who is the study for?
This trial is for people aged 18-40, with a BMI of 25 to 40 kg/m2. It's open to those who are overweight or obese and insulin resistant but generally healthy. Participants should be sedentary (exercising less than 30 minutes per week) or lean and physically active (3-5 aerobic sessions per week), with stable weight for the past three months.Check my eligibility
What is being tested?
The study compares fat and sugar metabolism in individuals before and after they complete either a supervised treadmill running program or a yoga training program. The goal is to understand how these activities affect insulin resistance, which can lead to type 2 diabetes.See study design
What are the potential side effects?
While not explicitly listed, potential side effects may include typical exercise-related risks such as muscle strain, fatigue, joint pain from the running program; yoga might cause muscle soreness or stretching-related injuries.

TrainMeUpMN Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I am overweight or obese, have insulin resistance, a stable weight, and exercise less than 30 minutes a week.
Select...
I am between 18 and 40 years old and can make my own medical decisions.

TrainMeUpMN Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~before and after exercise program (exercise program will take 16 weeks, expected average for evaluation will be 20 weeks)
This trial's timeline: 3 weeks for screening, Varies for treatment, and before and after exercise program (exercise program will take 16 weeks, expected average for evaluation will be 20 weeks) for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Differences in insulin sensitivity between groups
Secondary outcome measures
Differences in fitness level between groups
Other outcome measures
Differences in body composition between groups

TrainMeUpMN Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Obese or OverweightExperimental Treatment2 Interventions
Running Program Yoga Program
Group II: Lean TrainedActive Control1 Intervention
Metabolic control
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Yoga Program
2022
N/A
~120

Find a Location

Who is running the clinical trial?

University of MinnesotaLead Sponsor
1,377 Previous Clinical Trials
1,588,232 Total Patients Enrolled
National Institutes of Health (NIH)NIH
2,696 Previous Clinical Trials
6,952,524 Total Patients Enrolled
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)NIH
2,356 Previous Clinical Trials
4,315,002 Total Patients Enrolled

Media Library

Running Program Clinical Trial Eligibility Overview. Trial Name: NCT02150889 — N/A
Lean Trained Subjects Research Study Groups: Obese or Overweight, Lean Trained
Lean Trained Subjects Clinical Trial 2023: Running Program Highlights & Side Effects. Trial Name: NCT02150889 — N/A
Running Program 2023 Treatment Timeline for Medical Study. Trial Name: NCT02150889 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there opportunities for participation in this trial still available?

"Clinicaltrials.gov documents this particular research study as no longer recruiting, with the initial posting dating back to July 1st 2014 and its last update on November 14th 2022. However, there are presently 1160 different clinical trials searching for participants."

Answered by AI

What are the prerequisites for enrolling in this experiment?

"To be eligible, potential participants must possess a BMI in the overweight range and fall between 18-40 years old. Approximately 64 individuals are being sought for this clinical trial."

Answered by AI

Is the recruitment pool for this experiment open to those aged seventy-five and up?

"Adults aged 18 to 40 who meet the study's criteria are eligible for this trial. In contrast, there are 103 trials available for minors and 574 options suited to seniors."

Answered by AI

Who else is applying?

What state do they live in?
New Hampshire
Other
Minnesota
Georgia
How old are they?
18 - 65
What site did they apply to?
University of Minnesota
What portion of applicants met pre-screening criteria?
Did not meet criteria
Met criteria
How many prior treatments have patients received?
3+

Why did patients apply to this trial?

Diabetes type 2 and need for exercise.
PatientReceived no prior treatments
Recent research and studies
~6 spots leftby Apr 2025