Journey II for Osteoarthritis

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Edmonton Bone and Joint Centre, Edmonton, CanadaOsteoarthritisJourney II - Device
Eligibility
50 - 75
All Sexes
What conditions do you have?
Select

Study Summary

This trial will compare three different types of knee replacements to see which is most effective in terms of movement, pain, and function.

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

6 Primary · 8 Secondary · Reporting Duration: 2 years post-operative

1 year post-operative
Cadence during level treadmill walking
Knee
Max moment of knee flexion-extension during level treadmill walking
Knee
Max velocity of knee flexion-extension during level treadmill walking
Stride length during level treadmill walking
Walking velocity during level treadmill walking
knee abduction-adduction range of motion (ROM) during level treadmill walking
knee flexion-extension range of motion (ROM) during level treadmill walking
2 years post-operative
Euro-Quality of Life five dimensions questionnaire (EQ-5D)
Forgotten Joint Score
The new Knee Society Clinical Rating Scores (KSCRS)
UCLA activity-level rating (UCLA)
Knee

Trial Safety

Trial Design

3 Treatment Groups

Zimmer
1 of 3
Stryker
1 of 3
Journey II
1 of 3

Active Control

Experimental Treatment

60 Total Participants · 3 Treatment Groups

Primary Treatment: Journey II · No Placebo Group · N/A

Journey II
Device
Experimental Group · 1 Intervention: Journey II · Intervention Types: Device
Zimmer
Device
ActiveComparator Group · 1 Intervention: Zimmer · Intervention Types: Device
Stryker
Device
ActiveComparator Group · 1 Intervention: Stryker · Intervention Types: Device

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: 2 years post-operative

Who is running the clinical trial?

University of AlbertaLead Sponsor
823 Previous Clinical Trials
377,153 Total Patients Enrolled
1 Trials studying Osteoarthritis of the Knee
120 Patients Enrolled for Osteoarthritis of the Knee

Eligibility Criteria

Age 50 - 75 · All Participants · 5 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
You have been diagnosed with a type of joint disease called Non-Inflammatory Degenerative Joint Disease.
You need a specific type of knee replacement surgery called primary posterior-stabilized total knee replacement.

Frequently Asked Questions

Is this research endeavor presently searching for new participants?

"According to clinicaltrials.gov, this medical study has opened up recruitment for participants and was first published on the 9th of September in 2019. It has received its most recent update on August 11th 2022." - Anonymous Online Contributor

Unverified Answer

How many volunteers are being recruited for this medical trial?

"Affirmative. According to clinicaltrials.gov, this research is actively recruiting patients since it was first posted in September 2019 and then updated last August 2022. There are 60 positions open at a single medical centre." - Anonymous Online Contributor

Unverified Answer

Is it possible for me to participate in this experiment?

"This clinical trial is searching for 60 people between the ages of 50 to 75 who have osteoarthritis, knee. To be included in this study they must adhere to several conditions including: being a potential candidate for posterior-stabilized total knee replacement surgery, giving signed approval via an informed consent form, not being pregnant or male aged over 50 and under 75 years old at time of implantation procedure, having been diagnosed with Non Inflammatory Degenerative Joint Disease (NIDJD), and demonstrating commitment towards postoperative evaluations and rehabilitation sessions." - Anonymous Online Contributor

Unverified Answer

Does this clinical experiment have an upper age limit for participants?

"The eligibility requirements for this medical trial specify that all candidates must be in between the ages of 50 and 75." - Anonymous Online Contributor

Unverified Answer

What is the ultimate aim of this research endeavor?

"Over the course of one year post-operation, primary outcomes will be measured in terms of max velocity of knee abduction-adduction during level treadmill walking. Secondary measurements include walking velocities (as m/s) through a Computer Assisted Rehabilitation Environment (CAREN), The Knee Society Clinical Rating Scores, and UCLA activity-level rating scores ranging from 1 to 10." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.